Vasiliki E Georgakopoulou1,2, Nikolaos Garmpis3,4, Christos Damaskos5,6, Serena Valsami7, Dimitrios Dimitroulis3, Evangelos Diamantis8, Paraskevi Farmaki9, Chrysovalantis V Papageorgiou1, Sotiria Makrodimitri1, Nikolaos Gravvanis10, Stamatis Velonias10, Pagona Sklapani11, Nikolaos Trakas12, Efstathios A Antoniou3,4, Konstantinos Kontzoglou3,4, Lampros Nikolidakis13, Zoi Damaskou13, Athanasios Syllaios14, Georgios Marinos15, Georgia Vogiatzi15, Georgia-Eleni Korrou15, Georgios Kyriakos16, Lourdes-Victoria Quiles-Sanchez17, Alexandros Patsouras18, Dimitrios Lamprinos15, Athanasia Stelianidi9, Spyridon Savvanis19, Anna Garmpi20. 1. Department of Pulmonology, Laiko General Hospital, Athens, Greece. 2. First Department of Pulmonology, Sismanogleio Hospital, Athens, Greece. 3. Second Department of Propedeutic Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 4. N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 5. N.S. Christeas Laboratory of Experimental Surgery and Surgical Research, Medical School, National and Kapodistrian University of Athens, Athens, Greece; x_damaskos@yahoo.gr. 6. Renal Transplantation Unit, Laiko General Hospital, Athens, Greece. 7. Blood Transfusion Department, Aretaieion Hospital, Medical School, National and Kapodistrian Athens University, Athens, Greece. 8. Department of Endocrinology and Diabetes Center, G. Gennimatas General Hospital, Athens, Greece. 9. First Department of Pediatrics, Agia Sofia Children's Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 10. Health Center Peristeriou, Peristeri, Greece. 11. Department of Cytology, Mitera-Hygeia Hospital, Athens, Greece. 12. Biochemistry Department, Sismanogleio Hospital, Athens, Greece. 13. Department of Internal Medicine, Ygeias Melathron Hospital, Athens, Greece. 14. First Department of Surgery, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece. 15. Emergency Department, Laiko General Hospital, Athens, Greece. 16. Seccion de Endocrinologia y Nutrition, Hospital General Universitario Santa Lucia, Cartagena, Spain. 17. Centro de Salud Jesús Marín, Murcia, Spain. 18. Second Department of Internal Medicine, Tzanio General Hospital, Piraeus, Greece. 19. Department of Internal Medicine, Elpis General Hospital, Athens, Greece. 20. First Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Abstract
BACKGROUND/AIM: Eosinophils are blood cells responsible for response against parasites and allergens. Eosinophil to lymphocyte ratio (ELR) is a biomarker for inflammatory conditions. Our aim was to evaluate the role of eosinophils and ELR in COVID-19 patients. PATIENTS AND METHODS: The study included 96 patients hospitalized with COVID-19. They were classified into moderate to severe cases and critical cases. Eosinophils and ELR were determined in both groups, in patients that died or survived and were correlated to duration of hospitalization. RESULTS: There was a statistically significant decrease in eosinophils and ELR between patients that died and patients that survived (p<0.05), and in mean values of the two biomarkers (p<0.05 for eosinophils and p<0.05 for ELR) between patients hospitalized for more or less than 15 days among those with moderate to severe disease. CONCLUSION: Lower eosinophil counts and ERL could probably predict worse outcome in COVID-19 patients. Copyright
BACKGROUND/AIM: Eosinophils are blood cells responsible for response against parasites and allergens. Eosinophil to lymphocyte ratio (ELR) is a biomarker for inflammatory conditions. Our aim was to evaluate the role of eosinophils and ELR in COVID-19 patients. PATIENTS AND METHODS: The study included 96 patients hospitalized with COVID-19. They were classified into moderate to severe cases and critical cases. Eosinophils and ELR were determined in both groups, in patients that died or survived and were correlated to duration of hospitalization. RESULTS: There was a statistically significant decrease in eosinophils and ELR between patients that died and patients that survived (p<0.05), and in mean values of the two biomarkers (p<0.05 for eosinophils and p<0.05 for ELR) between patients hospitalized for more or less than 15 days among those with moderate to severe disease. CONCLUSION: Lower eosinophil counts and ERL could probably predict worse outcome in COVID-19 patients. Copyright
Authors: Amali E Samarasinghe; Rossana C N Melo; Susu Duan; Kim S LeMessurier; Swantje Liedmann; Sherri L Surman; James J Lee; Julia L Hurwitz; Paul G Thomas; Jonathan A McCullers Journal: J Immunol Date: 2017-03-10 Impact factor: 5.422
Authors: Armando S Flores-Torres; Mario C Salinas-Carmona; Eva Salinas; Adrian G Rosas-Taraco Journal: Viral Immunol Date: 2019-05-29 Impact factor: 2.257
Authors: Vasiliki E Georgakopoulou; Panagiotis Lembessis; Charalampos Skarlis; Aikaterini Gkoufa; Nikolaos V Sipsas; Clio P Mavragani Journal: Front Med (Lausanne) Date: 2022-03-17