Literature DB >> 33402513

Clinical Spectrum and Outcomes of Neonatal Necrotizing Enterocolitis.

PrzemysŁaw GaŁĄzka1,2, Magdalena Chrzanowska3, Jan StyczyŃski2.   

Abstract

BACKGROUND/AIM: The objective of the study was analysis of risk factors associated with outcome of necrotizing enterocolitis (NEC) in infants in a single-center study. PATIENTS AND METHODS: All consecutive infants hospitalized for NEC over a period of 6 years were retrospectively analyzed for clinical course, infections, treatment and outcome.
RESULTS: Out of 76 patients, surgical management was applied in 56 (53 exploratory laparotomy, three initial peritoneal drain placement) and in 20 there was only a conservative approach. Segmental intestinal resection was performed in 41 patients. Survival from NEC in our cohort was 79%. We found that independent adverse risk factors of outcome of newborns and infants with NEC were gut perforation, infection, abdominal wall erythema, and development of acute kidney injury.
CONCLUSION: We underline the value of both surgical and conservative approach with careful management in this cohort of patients. Copyright
© 2021, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Entities:  

Keywords:  Newborns; infants; minimally invasive surgery; necrotizing enterocolitis

Mesh:

Year:  2021        PMID: 33402513      PMCID: PMC7880741          DOI: 10.21873/invivo.12295

Source DB:  PubMed          Journal:  In Vivo        ISSN: 0258-851X            Impact factor:   2.155


  18 in total

1.  Laparoscopy to Assist Surgical Decisions Related to Necrotizing Enterocolitis in Preterm Neonates.

Authors:  Kristine Bach Korsholm Knudsen; Jorgen Thorup; Thomas Thymann; Rune Strandby; Nikolaj Nerup; Michael Patrick Achiam; Torsten Lauritsen; Lars Bo Svendsen; Lene Buelund; Per Torp Sangild; Inge Botker Rasmussen Ifaoui
Journal:  J Laparoendosc Adv Surg Tech A       Date:  2019-12-23       Impact factor: 1.878

Review 2.  Minimally Invasive Surgery in Pediatric Oncology: Proposal of Guidelines.

Authors:  Przemyslaw Galazka; Krzysztof Czyzewski; Agata Marjanska; Irena Daniluk-Matras; Jan Styczynski
Journal:  Anticancer Res       Date:  2019-11       Impact factor: 2.480

3.  Increased incidence of necrotizing enterocolitis in the Netherlands after implementation of the new Dutch guideline for active treatment in extremely preterm infants: Results from three academic referral centers.

Authors:  Fardou H Heida; Lisanne Stolwijk; Marie-Louise H J Loos; Stannie J van den Ende; Wes Onland; Frank A M van den Dungen; Elisabeth M W Kooi; Arend F Bos; Jan B F Hulscher; Roel Bakx
Journal:  J Pediatr Surg       Date:  2016-11-14       Impact factor: 2.545

4.  Acute kidney injury in newborns with necrotizing enterocolitis: risk factors and mortality.

Authors:  Carlos Sánchez; Miguel A García; Ben D Valdés
Journal:  Bol Med Hosp Infant Mex       Date:  2019

Review 5.  Necrotizing enterocolitis: It's not all in the gut.

Authors:  Alissa L Meister; Kim K Doheny; R Alberto Travagli
Journal:  Exp Biol Med (Maywood)       Date:  2019-12-06

6.  Coming full circle: an evidence-based definition of the timing and type of surgical management of very low-birth-weight (<1000 g) infants with signs of acute intestinal perforation.

Authors:  Joseph J Tepas; Renu Sharma; Mark L Hudak; Robert D Garrison; Pam Pieper
Journal:  J Pediatr Surg       Date:  2006-02       Impact factor: 2.545

7.  Neonatal necrotizing enterocolitis. Therapeutic decisions based upon clinical staging.

Authors:  M J Bell; J L Ternberg; R D Feigin; J P Keating; R Marshall; L Barton; T Brotherton
Journal:  Ann Surg       Date:  1978-01       Impact factor: 12.969

8.  Intestinal failure after necrotising enterocolitis: incidence and risk factors in a Swedish population-based longitudinal study.

Authors:  Tomas Sjoberg Bexelius; Margareta Ahle; Anders Elfvin; Oscar Björling; Jonas F Ludvigsson; Roland E Andersson
Journal:  BMJ Paediatr Open       Date:  2018-12-04

Review 9.  Necrotizing enterocolitis: treatment based on staging criteria.

Authors:  M C Walsh; R M Kliegman
Journal:  Pediatr Clin North Am       Date:  1986-02       Impact factor: 3.278

Review 10.  Protective effects of different doses of human milk on neonatal necrotizing enterocolitis.

Authors:  Baoquan Zhang; Wenlong Xiu; Yue Dai; Changyi Yang
Journal:  Medicine (Baltimore)       Date:  2020-09-11       Impact factor: 1.817

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