M Isabel Hervella1, Concepción Carratalá-Munuera2, Domingo Orozco-Beltrán2, Adriana López-Pineda3, Vicente Bertomeu-González4, Vicente F Gil-Guillén2, Reyes Pascual5, José A Quesada2. 1. Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain; Centro de Atención Primaria Mutxamel, Conselleria de Sanitat Universal i Salut Pública, Alicante, Spain. 2. Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain; Departamento de Medicina Clínica, Universidad Miguel Hernández, San Juan de Alicante, Alicante, Spain. 3. Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain; Departamento de Medicina Clínica, Universidad Miguel Hernández, San Juan de Alicante, Alicante, Spain. Electronic address: adriannalp@hotmail.com. 4. Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain; Sección de Cardiología, Hospital Universitario de San Juan de Alicante, San Juan de Alicante, Alicante, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain. 5. Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain.
Abstract
INTRODUCTION AND OBJECTIVES: Ischemic heart disease (IHD) is the leading cause of death and one of the leading causes of disability. The aim of this study was to analyze trends in premature mortality due to IHD in patients younger than 75 years in Spain from 1998 to 2018 by region. METHODS: Observational study of temporal trends in premature mortality due to IHD in Spain by region and sex from 1998 to 2018. The study population included resident citizens aged between 0 and 74 years. The data sources were the continuous population register and the mortality registry of the National Institute of Statistics. We calculated age-adjusted mortality rates and their average annual percent change estimated by Poisson models. RESULTS: During the study period, mortality rates due to IHD decreased, both in the country as a whole and by provinces (53% in men and 61% in women), with an average annual percent change of -3.92% and -5.07%, respectively. In the first year (1998), mortality was unequally distributed among provinces, with higher mortality in the south of Spain. CONCLUSIONS: Premature mortality due to IHD significantly decreased in Spain during the study period in both sexes to roughly half of initial cases. This decrease was statistically significant in almost all regions. Interprovincial differences in mortality and their variation also decreased in recent years.
INTRODUCTION AND OBJECTIVES:Ischemic heart disease (IHD) is the leading cause of death and one of the leading causes of disability. The aim of this study was to analyze trends in premature mortality due to IHD in patients younger than 75 years in Spain from 1998 to 2018 by region. METHODS: Observational study of temporal trends in premature mortality due to IHD in Spain by region and sex from 1998 to 2018. The study population included resident citizens aged between 0 and 74 years. The data sources were the continuous population register and the mortality registry of the National Institute of Statistics. We calculated age-adjusted mortality rates and their average annual percent change estimated by Poisson models. RESULTS: During the study period, mortality rates due to IHD decreased, both in the country as a whole and by provinces (53% in men and 61% in women), with an average annual percent change of -3.92% and -5.07%, respectively. In the first year (1998), mortality was unequally distributed among provinces, with higher mortality in the south of Spain. CONCLUSIONS: Premature mortality due to IHD significantly decreased in Spain during the study period in both sexes to roughly half of initial cases. This decrease was statistically significant in almost all regions. Interprovincial differences in mortality and their variation also decreased in recent years.