Literature DB >> 33401653

Toxocariasis in a Child with Autism Spectrum Disorder.

Filippo Pieroni1, Francesco Massei2, Maria Vittoria Micheletti2, Laura Luti2, Emanuela De Marco2, Alessandra Ludovisi3, Gabriella Casazza2, Fabrizio Bruschi4,5.   

Abstract

A boy affected by autism spectrum disorder was admitted for persistent high fever, without shiver, for two weeks. The boy referred to abdominal pain, in the first week of fever, and to mild anorexia in the last days before admittance to our hospital centre. The father reported that the boy suffered by geophagia and coprophagia and he has been going to a didactical farm (where he has been exposed to several kinds of animals) to improve his neuropsychiatric condition. Blood analysis shows severe eosinophilia and high levels of total IgE, and abdominal echocardiography showed hepatic lesions. Enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) confirmed the suspicion of toxocariasis, linked to the habit of the boy to ingest ground or animal faeces in a didactic farm frequented by the boy. Treatment with albendazole and prednisone was administered with a rapid improvement of the symptoms and the laboratory findings and significant reduction of the hepatic lesion.

Entities:  

Keywords:  Toxocara canis; autism; severe eosinophilia; toxocariasis

Mesh:

Substances:

Year:  2021        PMID: 33401653      PMCID: PMC7795894          DOI: 10.3390/ijerph18010283

Source DB:  PubMed          Journal:  Int J Environ Res Public Health        ISSN: 1660-4601            Impact factor:   3.390


  10 in total

1.  Nematode intestinal parasites of children in rural Guinea, Africa: prevalence and relationship to geophagia.

Authors:  L T Glickman; A O Camara; N W Glickman; G P McCabe
Journal:  Int J Epidemiol       Date:  1999-02       Impact factor: 7.196

2.  Public understanding of toxocariasis.

Authors:  D L Wells
Journal:  Public Health       Date:  2007-01-16       Impact factor: 2.427

3.  Toxocara canis infection: an important and neglected environmental risk factor for asthma?

Authors:  P J Cooper
Journal:  Clin Exp Allergy       Date:  2008-01-30       Impact factor: 5.018

Review 4.  Neurotoxocariasis: a systematic literature review.

Authors:  S Deshayes; J Bonhomme; Arnaud de La Blanchardière
Journal:  Infection       Date:  2016-03-23       Impact factor: 3.553

Review 5.  Human toxocariasis.

Authors:  Guangxu Ma; Celia V Holland; Tao Wang; Andreas Hofmann; Chia-Kwung Fan; Rick M Maizels; Peter J Hotez; Robin B Gasser
Journal:  Lancet Infect Dis       Date:  2017-08-03       Impact factor: 25.071

6.  Toxocara in sandpits of public playgrounds and kindergartens in Flanders (Belgium).

Authors:  Merijn Vanhee; Anne-Catherine Dalemans; Jasmine Viaene; Lies Depuydt; Edwin Claerebout
Journal:  Vet Parasitol Reg Stud Reports       Date:  2016-03-23

Review 7.  Toxocara eggs in public places worldwide - A systematic review and meta-analysis.

Authors:  Y Fakhri; R B Gasser; A Rostami; C K Fan; S M Ghasemi; M Javanian; M Bayani; B Armoon; B Moradi
Journal:  Environ Pollut       Date:  2018-07-27       Impact factor: 8.071

8.  Toxocara canis infection of children: epidemiologic and neuropsychologic findings.

Authors:  M Marmor; L Glickman; F Shofer; L A Faich; C Rosenberg; B Cornblatt; S Friedman
Journal:  Am J Public Health       Date:  1987-05       Impact factor: 9.308

Review 9.  Toxocariasis: clinical aspects, epidemiology, medical ecology, and molecular aspects.

Authors:  Dickson Despommier
Journal:  Clin Microbiol Rev       Date:  2003-04       Impact factor: 26.132

10.  Reduced cognitive function in children with toxocariasis in a nationally representative sample of the United States.

Authors:  Michael G Walsh; M A Haseeb
Journal:  Int J Parasitol       Date:  2012-11-01       Impact factor: 3.981

  10 in total

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