James Maguire1,2, Nathan Mifsud1,2, Natalie Seiler1,2, Tony Nguyen1,2, Holly Sizer1,2, Patrick McGorry1,2, Brian O'Donoghue3,4. 1. Orygen, 35 Poplar rd, Parkville, VIC, 3052, Australia. 2. Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. 3. Orygen, 35 Poplar rd, Parkville, VIC, 3052, Australia. brian.odonoghue@orygen.org.au. 4. Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia. brian.odonoghue@orygen.org.au.
Abstract
BACKGROUND: Certain migrant groups have been identified as being at increased risk of developing a psychotic disorder, but there is limited research on the outcomes for migrants who develop a first episode of psychosis (FEP). We investigated symptomatic outcomes (remission and relapse rates), functional outcomes (occupational status and relationships) and service utilization (hospital admission and engagement). METHODS: Young people, aged between 15 and 24, who presented with FEP to the Early Psychosis Prevention and Intervention Centre (EPPIC) at Orygen between 01.01.11 and 31.12.16 were included. Place of birth was recorded at the time of presentation. To determine remission, symptoms were scored at three-month intervals using the short-form Scale for the Assessment of Positive Symptoms. RESULTS: A total of 1220 young people presented with FEP over the six-year period (mean age = 19.6 ± 2.8). Of these, 58.1% were male and 24.0% were first-generation migrants. While there was no difference in overall rates of admission after presentation, migrants were more likely to have an involuntary admission after presentation (31.4% vs. 24.6%, aHR = 1.54, 95% CI [1.19, 2.01]) and this risk was greatest for African migrants (HR = 1.98, 95% C.I. [1.37, 2.86]. The rates of remission and relapse were similar in migrants and those born in Australia and there was no difference in functional outcomes, such as employment rates at follow-up. DISCUSSION: The outcomes for migrants who experience FEP appear to be largely similar to those for the Australian-born population. Our finding that a greater rate of involuntary admission for migrants at presentation supports existing literature and needs further exploration to improve clinical care.
BACKGROUND: Certain migrant groups have been identified as being at increased risk of developing a psychotic disorder, but there is limited research on the outcomes for migrants who develop a first episode of psychosis (FEP). We investigated symptomatic outcomes (remission and relapse rates), functional outcomes (occupational status and relationships) and service utilization (hospital admission and engagement). METHODS: Young people, aged between 15 and 24, who presented with FEP to the Early Psychosis Prevention and Intervention Centre (EPPIC) at Orygen between 01.01.11 and 31.12.16 were included. Place of birth was recorded at the time of presentation. To determine remission, symptoms were scored at three-month intervals using the short-form Scale for the Assessment of Positive Symptoms. RESULTS: A total of 1220 young people presented with FEP over the six-year period (mean age = 19.6 ± 2.8). Of these, 58.1% were male and 24.0% were first-generation migrants. While there was no difference in overall rates of admission after presentation, migrants were more likely to have an involuntary admission after presentation (31.4% vs. 24.6%, aHR = 1.54, 95% CI [1.19, 2.01]) and this risk was greatest for African migrants (HR = 1.98, 95% C.I. [1.37, 2.86]. The rates of remission and relapse were similar in migrants and those born in Australia and there was no difference in functional outcomes, such as employment rates at follow-up. DISCUSSION: The outcomes for migrants who experience FEP appear to be largely similar to those for the Australian-born population. Our finding that a greater rate of involuntary admission for migrants at presentation supports existing literature and needs further exploration to improve clinical care.
Authors: Scott Eaton; Benjamin Harrap; Linglee Downey; Kristen Thien; Meghan Bowtell; Melissa Bardell-Williams; Aswin Ratheesh; Patrick McGorry; Brian O'Donoghue Journal: Schizophr Res Date: 2019-05-24 Impact factor: 4.939
Authors: Helen Krstev; Steve Carbone; Susy M Harrigan; Christina Curry; Kathryn Elkins; Patrick D McGorry Journal: Soc Psychiatry Psychiatr Epidemiol Date: 2004-09 Impact factor: 4.328
Authors: Brian O'Donoghue; Linglee Downey; Scott Eaton; Nathan Mifsud; James B Kirkbride; Patrick McGorry Journal: Psychol Med Date: 2020-01-30 Impact factor: 7.723
Authors: G Baudin; O Godin; M Lajnef; B Aouizerate; F Berna; L Brunel; D Capdevielle; I Chereau; J M Dorey; C Dubertret; J Dubreucq; C Faget; G Fond; F Gabayet; H Laouamri; C Lancon; Y Le Strat; A M Tronche; D Misdrahi; R Rey; C Passerieux; A Schandrin; M Urbach; P Vidalhet; P M Llorca; F Schürhoff Journal: Schizophr Res Date: 2016-05-18 Impact factor: 4.939