| Literature DB >> 33397999 |
Janak Gaire1, Justin A Varholick2, Sabhya Rana3, Michael D Sunshine3, Sylvain Doré4, W Brad Barbazuk5, David D Fuller3,6, Malcolm Maden5, Chelsey S Simmons7,8.
Abstract
The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.Entities:
Year: 2021 PMID: 33397999 PMCID: PMC7782534 DOI: 10.1038/s41536-020-00111-1
Source DB: PubMed Journal: NPJ Regen Med ISSN: 2057-3995