Literature DB >> 33397999

Spiny mouse (Acomys): an emerging research organism for regenerative medicine with applications beyond the skin.

Janak Gaire1, Justin A Varholick2, Sabhya Rana3, Michael D Sunshine3, Sylvain Doré4, W Brad Barbazuk5, David D Fuller3,6, Malcolm Maden5, Chelsey S Simmons7,8.   

Abstract

The spiny mouse (Acomys species) has emerged as an exciting research organism due to its remarkable ability to undergo scarless regeneration of skin wounds and ear punches. Excitingly, Acomys species demonstrate scar-free healing in a wide-range of tissues beyond the skin. In this perspective article, we discuss published findings from a variety of tissues to highlight how this emerging research organism could shed light on numerous clinically relevant human diseases. We also discuss the challenges of working with this emerging research organism and suggest strategies for future Acomys-inspired research.

Entities:  

Year:  2021        PMID: 33397999      PMCID: PMC7782534          DOI: 10.1038/s41536-020-00111-1

Source DB:  PubMed          Journal:  NPJ Regen Med        ISSN: 2057-3995


  45 in total

Review 1.  Animal models of skin regeneration.

Authors:  Barbara Gawronska-Kozak; Anna Grabowska; Marta Kopcewicz; Anna Kur
Journal:  Reprod Biol       Date:  2014-01-17       Impact factor: 2.376

2.  Regeneration-Competent and -Incompetent Murids Differ in Neutrophil Quantity and Function.

Authors:  Jennifer L Cyr; Thomas R Gawriluk; John M Kimani; Balázs Rada; Wendy T Watford; Stephen G Kiama; Ashley W Seifert; Vanessa O Ezenwa
Journal:  Integr Comp Biol       Date:  2019-11-01       Impact factor: 3.326

3.  Location of injury influences the mechanisms of both regeneration and repair within the MRL/MpJ mouse.

Authors:  Alice H M Beare; Anthony D Metcalfe; Mark W J Ferguson
Journal:  J Anat       Date:  2006-10       Impact factor: 2.610

4.  First evidence of a menstruating rodent: the spiny mouse (Acomys cahirinus).

Authors:  Nadia Bellofiore; Stacey J Ellery; Jared Mamrot; David W Walker; Peter Temple-Smith; Hayley Dickinson
Journal:  Am J Obstet Gynecol       Date:  2016-08-05       Impact factor: 8.661

5.  The Cairo spiny mouse Acomys cahirinus shows a strong affinity to the Mongolian gerbil Meriones unguiculatus.

Authors:  S I Agulnik; L M Silver
Journal:  Mol Biol Evol       Date:  1996-01       Impact factor: 16.240

6.  Cellular events during scar-free skin regeneration in the spiny mouse, Acomys.

Authors:  Jason O Brant; Jung H Yoon; Trey Polvadore; William Brad Barbazuk; Malcolm Maden
Journal:  Wound Repair Regen       Date:  2016-01-19       Impact factor: 3.617

7.  The Biology and Husbandry of the African Spiny Mouse (Acomys cahirinus) and the Research Uses of a Laboratory Colony.

Authors:  Cheryl L Haughton; Thomas R Gawriluk; Ashley W Seifert
Journal:  J Am Assoc Lab Anim Sci       Date:  2016-01       Impact factor: 1.232

8.  Unique behavior of dermal cells from regenerative mammal, the African Spiny Mouse, in response to substrate stiffness.

Authors:  Daniel C Stewart; P Nicole Serrano; Andrés Rubiano; Ryosuke Yokosawa; Justin Sandler; Marah Mukhtar; Jason O Brant; Malcolm Maden; Chelsey S Simmons
Journal:  J Biomech       Date:  2018-10-14       Impact factor: 2.712

9.  Ear wound regeneration in the African spiny mouse Acomys cahirinus.

Authors:  Dino Matias Santos; Ana Martins Rita; Ignasi Casanellas; Adélia Brito Ova; Inês Maria Araújo; Deborah Power; Gustavo Tiscornia
Journal:  Regeneration (Oxf)       Date:  2016-03-09

10.  AP-1cFos/JunB/miR-200a regulate the pro-regenerative glial cell response during axolotl spinal cord regeneration.

Authors:  Keith Z Sabin; Peng Jiang; Micah D Gearhart; Ron Stewart; Karen Echeverri
Journal:  Commun Biol       Date:  2019-03-06
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  3 in total

1.  What is next in African neuroscience?

Authors:  Kirsten A Donald; Mahmoud Maina; Nilesh Patel; Carine Nguemeni; Wael Mohammed; Amina Abubakar; Matthew Brown; Raliza Stoyanova; Andrew Welchman; Natasha Walker; Alexis Willett; Symon M Kariuki; Anthony Figaji; Dan J Stein; Amadi O Ihunwo; William Daniels; Charles R Newton
Journal:  Elife       Date:  2022-06-22       Impact factor: 8.713

2.  Non-destructive monitoring of 3D cell cultures: new technologies and applications.

Authors:  Marilisa Cortesi; Emanuele Giordano
Journal:  PeerJ       Date:  2022-05-12       Impact factor: 3.061

Review 3.  Protein Hydrogels: The Swiss Army Knife for Enhanced Mechanical and Bioactive Properties of Biomaterials.

Authors:  Carla Huerta-López; Jorge Alegre-Cebollada
Journal:  Nanomaterials (Basel)       Date:  2021-06-24       Impact factor: 5.076

  3 in total

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