| Literature DB >> 33396602 |
Soo-Min Ok1,2,3, Donald Ho3, Tyler Lynd3, Yong-Woo Ahn1,2, Hye-Min Ju1,2, Sung-Hee Jeong1,2, Kyounga Cheon3.
Abstract
Candida species are common global opportunistic pathogens that could repeatedly and chronically cause oral mucosa infection and create an inflammatory environment, leading to organ dysfunction. Oral Candida infections may cause temporary or permanent damage to salivary glands, resulting in the destruction of acinar cells and the formation of scar tissue. Restricted function of the salivary glands leads to discomfort and diseases of the oral mucosa, such as dry mouth and associated infection. This narrative review attempts to summarize the anatomy and function of salivary glands, the associations between Candida and saliva, the effects of Candida infection on salivary glands, and the treatment strategies. Overall, clinicians should proactively manage Candida infections by educating patients on oral hygiene management for vulnerable populations, conducting frequent checks for a timely diagnosis, and providing an effective treatment plan.Entities:
Keywords: oral candidiasis; saliva; salivary gland; treatment
Year: 2020 PMID: 33396602 DOI: 10.3390/jcm10010097
Source DB: PubMed Journal: J Clin Med ISSN: 2077-0383 Impact factor: 4.241