Hammouda Yassir1, Hicham Ngham2, Mouna Lyoubi3, Reda Allah Abada4, Youssef Oukessou5, Mohammed Roubal6, Mohammed Mahtar7. 1. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: yassir1ham@gmail.com. 2. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: Hicham.ngham@gmail.com. 3. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: mounalyoubi03@gmail.com. 4. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: RedaCHU1234@gmail.com. 5. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: youssef.chucasa@gmail.com. 6. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: mohammedchu1234@gmail.com. 7. ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Postal Address 20000, Casablanca, Morocco. Electronic address: mohammed.m.chu1234@gmail.com.
Abstract
INTRODUCTION: Rhabdomyosarcoma (RMS) is a malignant mesenchymal neoplasm uncommon in adults. PRESENTATION OF CASE: We report the case of an alveolar rhabdomyosarcoma in a rare location and in an adult. It concerns a 46-year-old woman with a mandibular location invading the parotid gland. The Immunohistochemical analysis revealed intense positivity for myogenin and desmin, favoring the diagnosis of alveolar rhabdomyosarcoma. The patient had a right hemi-mandibulectomy with parotidectomy and received chemotherapy with radiotherapy. The evolution was good up to 2 years postoperatively then the patient relapsed with a recurrence of tumour rapidly progressing and metastases in the cervical spine. DISCUSSION: RMS is an aggressive but rare disease that is one of the most common malignant head and neck tumors in children. The predilection sites of adult rhabdomyosarcoma are the extremities. Current treatment includes a combination of ablative surgery, chemotherapy, and radiation therapy. CONCLUSION: The prognosis of head and neck rhabdomyosarcomas in adults remains very poor given the often initially advanced stage of the disease and the high metastatic potential.
INTRODUCTION:Rhabdomyosarcoma (RMS) is a malignant mesenchymal neoplasm uncommon in adults. PRESENTATION OF CASE: We report the case of an alveolar rhabdomyosarcoma in a rare location and in an adult. It concerns a 46-year-old woman with a mandibular location invading the parotid gland. The Immunohistochemical analysis revealed intense positivity for myogenin and desmin, favoring the diagnosis of alveolar rhabdomyosarcoma. The patient had a right hemi-mandibulectomy with parotidectomy and received chemotherapy with radiotherapy. The evolution was good up to 2 years postoperatively then the patient relapsed with a recurrence of tumour rapidly progressing and metastases in the cervical spine. DISCUSSION: RMS is an aggressive but rare disease that is one of the most common malignant head and neck tumors in children. The predilection sites of adult rhabdomyosarcoma are the extremities. Current treatment includes a combination of ablative surgery, chemotherapy, and radiation therapy. CONCLUSION: The prognosis of head and neck rhabdomyosarcomas in adults remains very poor given the often initially advanced stage of the disease and the high metastatic potential.