Nergiz Ekmen1, Güray Can2, Ahmet Yozgat3, Hatice Can4, Muahammed Fatih Bayraktar5, Muhammed Emin Demirkol6, Meral Akdogan Kayhan7, Hadi Sasani8. 1. Gastroenterogy, Gazi university, Turkey. 2. Gastroenterology, Abant İzzet Baysal University, Turkey. 3. Gastroenterology, Ufuk University, Türkiye. 4. Nephrology, İnönü University, Turkey. 5. Cardiology, Abant Izzet Baysal University, Turkey. 6. Internal Medicine, Abant İzzet Baysal University, Turkey. 7. Gastroenterology, Ankara State Hospital, Turkey. 8. Radiology, Namık Kemal University, Turkey.
Abstract
Background and study's purpose: It was aimed to compare carotid intima media (CIMT) and epicardial adipose tissue (EAT) measurements, which are considered as markers in detecting early atherosclerosis, in healthy control and inflammatory bowel diseases (IBD). METHODS: In a total of 60 IBD patients (25 crohn disease and 35 ulcerative colitis) and 60 healthy patients as control group, were included in the study. The measurement of CIMT and EAT were performed by using echocardiography and ultrasonography, respectively. Statistical analysis was employed for the relationship between the parameters. MAIN RESULTS: The thickness of bilateral (right and left) CIMT and EAT were found to be significantly higher in IBD than those of the control group (P <0.05). There was a positive correlation between EAT and bilateral (right and left) CIMT in IBD patients (p<0,05). CONCLUSION: IBD is associated with increased thickness of EAT and CIMT. Because chronic inflammation in IBD may increase the risk of atherosclerotic heart disease, only measuring the thickness of EAT and CIMT can be used as an objective, easy, simple, affordable, non-invasive and accessible assessment method in order to screen this risk.
Background and study's purpose: It was aimed to compare carotid intima media (CIMT) and epicardial adipose tissue (EAT) measurements, which are considered as markers in detecting early atherosclerosis, in healthy control and inflammatory bowel diseases (IBD). METHODS: In a total of 60 IBDpatients (25 crohn disease and 35 ulcerative colitis) and 60 healthy patients as control group, were included in the study. The measurement of CIMT and EAT were performed by using echocardiography and ultrasonography, respectively. Statistical analysis was employed for the relationship between the parameters. MAIN RESULTS: The thickness of bilateral (right and left) CIMT and EAT were found to be significantly higher in IBD than those of the control group (P <0.05). There was a positive correlation between EAT and bilateral (right and left) CIMT in IBDpatients (p<0,05). CONCLUSION:IBD is associated with increased thickness of EAT and CIMT. Because chronic inflammation in IBD may increase the risk of atherosclerotic heart disease, only measuring the thickness of EAT and CIMT can be used as an objective, easy, simple, affordable, non-invasive and accessible assessment method in order to screen this risk.
Authors: Güray Can; Nergis Ekmen; Hatice Can; Muhammet Fatih Bayraktar; Muhammed Emin Demirkol; Meral Akdoğan Kayhan; Hadi Sasani Journal: Saudi J Gastroenterol Date: 2021 Sep-Oct Impact factor: 2.485