INTRODUCTION: Undifferentiated prostate cancer is a rare and aggressive disease, and no definitive therapeutic strategy for metastatic undifferentiated prostate cancer has been established. CASE PRESENTATION: We report the case of a 70-year-old man with undifferentiated prostate cancer and lymph node metastases. Following the patient's progression after platinum-based chemotherapy, we initiated treatment with docetaxel, which resulted in a partial response. The patient was alive for 42 months after initiation of docetaxel, maintaining relatively good quality of life with minimal hospital stay. CONCLUSION: Docetaxel may be a good therapeutic option for metastatic undifferentiated prostate cancer.
INTRODUCTION: Undifferentiated prostate cancer is a rare and aggressive disease, and no definitive therapeutic strategy for metastatic undifferentiated prostate cancer has been established. CASE PRESENTATION: We report the case of a 70-year-old man with undifferentiated prostate cancer and lymph node metastases. Following the patient's progression after platinum-based chemotherapy, we initiated treatment with docetaxel, which resulted in a partial response. The patient was alive for 42 months after initiation of docetaxel, maintaining relatively good quality of life with minimal hospital stay. CONCLUSION: Docetaxel may be a good therapeutic option for metastatic undifferentiated prostate cancer.
Authors: Marlene Troch; Oskar Koperek; Christian Scheuba; Karin Dieckmann; Martha Hoffmann; Bruno Niederle; Markus Raderer Journal: J Clin Endocrinol Metab Date: 2010-06-30 Impact factor: 5.958
Authors: Yong Sang Hong; Young Suk Park; Ho Yeong Lim; Jeeyun Lee; Tae Won Kim; Kyu-pyo Kim; Sun Young Kim; Ji Yeon Baek; Jee Hyun Kim; Keun-Wook Lee; Ik-Joo Chung; Sang-Hee Cho; Kyung Hee Lee; Sang Joon Shin; Hye Jin Kang; Dong Bok Shin; Sook Jung Jo; Jae Won Lee Journal: Lancet Oncol Date: 2012-10-10 Impact factor: 41.316
Authors: Daniel P Petrylak; Catherine M Tangen; Maha H A Hussain; Primo N Lara; Jeffrey A Jones; Mary Ellen Taplin; Patrick A Burch; Donna Berry; Carol Moinpour; Manish Kohli; Mitchell C Benson; Eric J Small; Derek Raghavan; E David Crawford Journal: N Engl J Med Date: 2004-10-07 Impact factor: 91.245
Authors: Ian F Tannock; Ronald de Wit; William R Berry; Jozsef Horti; Anna Pluzanska; Kim N Chi; Stephane Oudard; Christine Théodore; Nicholas D James; Ingela Turesson; Mark A Rosenthal; Mario A Eisenberger Journal: N Engl J Med Date: 2004-10-07 Impact factor: 91.245