Literature DB >> 33390809

A review of linc00673 as a novel lncRNA for tumor regulation.

Kunjie Zhu1,2, Zhaojian Gong3, Panchun Li3, Xianjie Jiang1,2, Zhaoyang Zeng1,2, Wei Xiong1,2, Jianjun Yu1.   

Abstract

Long non-coding RNAs (LncRNAs) act as regulators and play important roles in a variety of biological processes. These regulators constitute a huge information network among genes and participate in the pathophysiological process of human diseases. Increasing evidence has demonstrated that LncRNA, as an oncogene or tumor suppressor gene, is closely related to the occurrence and development of tumors. Linc00673 is a recently discovered LncRNA molecule that is dysregulated in several solid tumors. Moreover, its genetic polymorphism is believed to affect the susceptibility of a population to the corresponding cancer species. This article summarizes the role of Linc00673 in different human cancers and its molecular mechanisms with a focus on the characteristics of Linc00673 and the existing literature on it while highlighting the future research directions for Linc00673. Linc00673 has the potential to become a feasible clinical diagnostic and prognostic marker toward providing a new molecular therapeutic target for cancer patients. © The author(s).

Entities:  

Keywords:  Cancer; Diagnosis; LncRNA; Prognosis; SNP

Year:  2021        PMID: 33390809      PMCID: PMC7757132          DOI: 10.7150/ijms.48134

Source DB:  PubMed          Journal:  Int J Med Sci        ISSN: 1449-1907            Impact factor:   3.738


  3 in total

1.  Association of LINC00673 rs11655237 polymorphism with pediatric glioma susceptibility in a Chinese population.

Authors:  Zhuorong Zhang; Yihuan Huang; Ping Wu; Honghao Chen; Zhijian Deng; Gaoyan Deng; Yongqin Zheng; Guoyuan Li; Li Yuan; Le Li
Journal:  Transl Pediatr       Date:  2021-07

2.  Impact of Long Noncoding RNA LINC00673 Genetic Variants on Susceptibility to Diabetic Retinopathy.

Authors:  Chih-Chun Chuang; Yi-Sun Yang; Edy Kornelius; Chien-Ning Huang; Min-Yen Hsu; Chia-Yi Lee; Shun-Fa Yang
Journal:  Front Genet       Date:  2022-04-25       Impact factor: 4.772

Review 3.  Long non-coding RNAs are involved in alternative splicing and promote cancer progression.

Authors:  Jiawei Ouyang; Yu Zhong; Yijie Zhang; Liting Yang; Pan Wu; Xiangchan Hou; Fang Xiong; Xiayu Li; Shanshan Zhang; Zhaojian Gong; Yi He; Yanyan Tang; Wenling Zhang; Bo Xiang; Ming Zhou; Jian Ma; Yong Li; Guiyuan Li; Zhaoyang Zeng; Can Guo; Wei Xiong
Journal:  Br J Cancer       Date:  2021-11-08       Impact factor: 9.075

  3 in total

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