Literature DB >> 33389543

Lean NAFLD: an underrecognized and challenging disorder in medicine.

Sheila Maier1, Amanda Wieland2, Melanie Cree-Green3, Kristen Nadeau3, Shelby Sullivan4, Miguel A Lanaspa5, Richard J Johnson5, Thomas Jensen6,7.   

Abstract

Classically, Non-Alcoholic Fatty Liver Disease (NAFLD) has been thought to be driven by excessive weight gain and obesity. The overall greater awareness of this disorder has led to its recognition in patients with normal body mass index (BMI). Ongoing research has helped to better understand potential causes of Lean NAFLD, the risks for more advanced disease, and potential therapies. Here we review the recent literature on prevalence, risk factors, severity of disease, and potential therapeutic interventions.

Entities:  

Keywords:  Lean; Metabolic syndrome; Non-alcoholic fatty liver disease; Nonalcoholic Steatohepatitis; Nonobese; Nonoverweight

Mesh：

Year:  2021        PMID： 33389543      PMCID： PMC8893229          DOI： 10.1007/s11154-020-09621-1

Source DB:  PubMed          Journal:  Rev Endocr Metab Disord        ISSN： 1389-9155            Impact factor:   6.514


  125 in total

Review 1.  Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies.

Authors: 
Journal:  Lancet       Date:  2004-01-10       Impact factor: 79.321

2.  Kwashiorkor: a nutritional disease of children associated with a maize diet. 1935.

Authors:  Cicely D Williams; B M Oxon; H Lond
Journal:  Bull World Health Organ       Date:  2004-03-01       Impact factor: 9.408

3.  Hydroxysteroid 17-β dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease.

Authors:  Panu K Luukkonen; Taru Tukiainen; Anne Juuti; Henna Sammalkorpi; P A Nidhina Haridas; Onni Niemelä; Johanna Arola; Marju Orho-Melander; Antti Hakkarainen; Petri T Kovanen; Om Dwivedi; Leif Groop; Leanne Hodson; Amalia Gastaldelli; Tuulia Hyötyläinen; Matej Orešič; Hannele Yki-Järvinen
Journal:  JCI Insight       Date:  2020-03-12

Review 4.  Drug Development for Nonalcoholic Fatty Liver Disease: Landscape and Challenges.

Authors:  Prarthana Thiagarajan; Guruprasad P Aithal
Journal:  J Clin Exp Hepatol       Date:  2019-03-13

5.  Clinical and Metabolic Characterization of Lean Caucasian Subjects With Non-alcoholic Fatty Liver.

Authors:  Alexandra Feldman; Sebastian K Eder; Thomas K Felder; Lyudmyla Kedenko; Bernhard Paulweber; Andreas Stadlmayr; Ursula Huber-Schönauer; David Niederseer; Felix Stickel; Simon Auer; Elisabeth Haschke-Becher; Wolfgang Patsch; Christian Datz; Elmar Aigner
Journal:  Am J Gastroenterol       Date:  2016-08-16       Impact factor: 10.864

6.  Prevalence and Severity of Nonalcoholic Fatty Liver Disease in Non-Obese Patients: A Population Study Using Proton-Magnetic Resonance Spectroscopy.

Authors:  Jeremy Lok Wei; Jonathan Chung-Fai Leung; Thomson Chi-Wang Loong; Grace Lai-Hung Wong; David Ka-Wai Yeung; Ruth Suk-Mei Chan; Henry Lik-Yuen Chan; Angel Mei-Ling Chim; Jean Woo; Winnie Chiu-Wing Chu; Vincent Wai-Sun Wong
Journal:  Am J Gastroenterol       Date:  2015-07-28       Impact factor: 10.864

7.  High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.

Authors:  Takuji Ishimoto; Miguel A Lanaspa; Christopher J Rivard; Carlos A Roncal-Jimenez; David J Orlicky; Christina Cicerchi; Rachel H McMahan; Manal F Abdelmalek; Hugo R Rosen; Matthew R Jackman; Paul S MacLean; Christine P Diggle; Aruna Asipu; Shinichiro Inaba; Tomoki Kosugi; Waichi Sato; Shoichi Maruyama; Laura G Sánchez-Lozada; Yuri Y Sautin; James O Hill; David T Bonthron; Richard J Johnson
Journal:  Hepatology       Date:  2013-10-08       Impact factor: 17.425

8.  Fructose consumption as a risk factor for non-alcoholic fatty liver disease.

Authors:  Xiaosen Ouyang; Pietro Cirillo; Yuri Sautin; Shannon McCall; James L Bruchette; Anna Mae Diehl; Richard J Johnson; Manal F Abdelmalek
Journal:  J Hepatol       Date:  2008-03-10       Impact factor: 25.083

Review 9.  The role of PNPLA3 in health and disease.

Authors:  Piero Pingitore; Stefano Romeo
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2018-06-20       Impact factor: 4.698

10.  Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.

Authors:  Miguel A Lanaspa; Takuji Ishimoto; Nanxing Li; Christina Cicerchi; David J Orlicky; Philip Ruzycki; Philip Ruzicky; Christopher Rivard; Shinichiro Inaba; Carlos A Roncal-Jimenez; Elise S Bales; Christine P Diggle; Aruna Asipu; J Mark Petrash; Tomoki Kosugi; Shoichi Maruyama; Laura G Sanchez-Lozada; James L McManaman; David T Bonthron; Yuri Y Sautin; Richard J Johnson
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919
View more
  5 in total

1.  Clinical and Laboratory Characteristics of Normal Weight and Obese Individuals with Non-Alcoholic Fatty Liver Disease.

Authors:  Anca Trifan; Adrian Rotaru; Remus Stafie; Ermina Stratina; Sebastian Zenovia; Robert Nastasa; Laura Huiban; Tudor Cuciureanu; Cristina Muzîca; Stefan Chiriac; Irina Gîrleanu; Ana-Maria Sîngeap; Catalin Sfarti; Camelia Cojocariu; Carol Stanciu
Journal:  Diagnostics (Basel)       Date:  2022-03-24

2.  Oxidized High-Density Lipoprotein Shows a Stepwise Increase as Fibrosis Progresses in Patients with Nonalcoholic Fatty Liver Disease.

Authors:  Kouichi Miura; Naoshi Arai; Rie Goka; Naoki Morimoto; Shunji Watanabe; Norio Isoda; Hironori Yamamoto; Kazuhiko Kotani
Journal:  Antioxidants (Basel)       Date:  2021-02-04

3.  Positive association of nap duration with risk of non-alcoholic fatty liver disease in an occupational population in Guangdong Province, China: a cross-sectional study.

Authors:  Chang Hong; Chengkai Wu; Pengcheng Ma; Hao Cui; Liya Chen; Ruining Li; Qimei Li; Lin Zeng; Shengwu Liao; Lushan Xiao; Li Liu; Wenyuan Li
Journal:  BMC Gastroenterol       Date:  2022-04-12       Impact factor: 3.067

4.  Nonalcoholic Fatty Liver Disease and Associated Risk Factors in a Community-Based Sample of Mexican-Origin Adults.

Authors:  David O Garcia; Kristin E Morrill; Melissa Lopez-Pentecost; Edgar A Villavicencio; Rosa M Vogel; Melanie L Bell; Yann C Klimentidis; David G Marrero; Cynthia A Thomson
Journal:  Hepatol Commun       Date:  2022-01-25

5.  Clinical Factors Associated with Non-Obese Nonalcoholic Fatty Liver Disease Detected among US Adults in the NHANES 2017-2018.

Authors:  Zayd Adnan Razouki; Xiaotao Zhang; Jessica P Hwang; Natalia I Heredia
Journal:  J Clin Med       Date:  2022-07-22       Impact factor: 4.964
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.