Two-dimensional inorganic nanosheets: production and utility in the development of novel electrochemical (bio)sensors and gas-sensing applications.

This review (with 178 references) focuses on inorganic layered materials (ILMs) and the use of their two-dimensional nanosheets in the development of novel electrochemical (bio)sensors, analytical devices, and gas-phase sensing applications. The text is organized in three main sections including the presentation of the most important families of ILMs, a comprehensive outline of various "bottom-up", "top-down," and hydro(solvo)thermal methods that have been used for the production of ILM nanosheets, and finally an evaluative survey on their utility for the determination of analytes with interest in different sectors of contemporary analysis. Critical discussion on the effect of the production method on their electronic properties, the suitability of each nanomaterial in different sensing technologies along with an assessment of the performance of the (bio)sensors and devices that have been proposed within the last 5 years, is enclosed. The perspectives of further improving the utility of 2D inorganic nanosheets in sensing applications, in real-world samples, are also discussed.