D S Christensen1,2,3, T Flensborg-Madsen4, N E Andersen5,6, I B Rosenkær7,6, E L Mortensen4. 1. Department of Oncology, Aarhus University Hospital, Aarhus C, Denmark. dsc@oncology.au.dk. 2. Unit for Psychooncology and Health Psychology (Epos), Department of Psychology and Behavioural Science, Aarhus University, Bartholins Alle 11, Bld. 1351, 8000, Aarhus C, Denmark. dsc@oncology.au.dk. 3. Department of Public Health, Section of Environmental Health, University of Copenhagen, Copenhagen, Denmark. dsc@oncology.au.dk. 4. Department of Public Health, Section of Environmental Health, University of Copenhagen, Copenhagen, Denmark. 5. Mental Health Services, Copenhagen, Denmark. 6. Department of Psychology, University of Copenhagen, Copenhagen, Denmark. 7. AS3 Work and Care, Copenhagen, Denmark.
Abstract
PURPOSE: The present study examined the prospective association of neuroticism, extraversion and psychoticism with risk of hospital diagnosed mental disorder, examining intelligence as a potential confounder of this association. METHODS: A total of 1118 Danish men and women completed the Eysenck personality questionnaire at the mean age of 27 years. Information on psychiatric diagnoses was obtained by linking the study population to the national Danish psychiatric registers, and risk of diagnoses associated with each personality trait was examined using multiple Cox regression in models including the three personality traits unadjusted and adjusted for intelligence. Participants with diagnosis from a psychiatric department prior to the personality assessment were excluded. RESULTS: In total, 122 participants were diagnosed with a mental disorder during follow-up. Neuroticism significantly predicted risk of anxiety-, adjustment-, personality- and alcohol and substance abuse diagnoses. Extraversion did not significantly predict any diagnosis type, while psychoticism predicted a combined category of mood and anxiety diagnoses. Despite intelligence being a significant predictor of the majority of the included diagnoses, adjusting for intelligence did not substantially influence any trait-disorder associations. CONCLUSION: The results confirm high neuroticism as a prospective vulnerability factor for mental disorder and indicate high psychoticism to be a potential risk factor for mood and anxiety disorders. These associations are not confounded by intelligence.
PURPOSE: The present study examined the prospective association of neuroticism, extraversion and psychoticism with risk of hospital diagnosed mental disorder, examining intelligence as a potential confounder of this association. METHODS: A total of 1118 Danish men and women completed the Eysenck personality questionnaire at the mean age of 27 years. Information on psychiatric diagnoses was obtained by linking the study population to the national Danish psychiatric registers, and risk of diagnoses associated with each personality trait was examined using multiple Cox regression in models including the three personality traits unadjusted and adjusted for intelligence. Participants with diagnosis from a psychiatric department prior to the personality assessment were excluded. RESULTS: In total, 122 participants were diagnosed with a mental disorder during follow-up. Neuroticism significantly predicted risk of anxiety-, adjustment-, personality- and alcohol and substance abuse diagnoses. Extraversion did not significantly predict any diagnosis type, while psychoticism predicted a combined category of mood and anxiety diagnoses. Despite intelligence being a significant predictor of the majority of the included diagnoses, adjusting for intelligence did not substantially influence any trait-disorder associations. CONCLUSION: The results confirm high neuroticism as a prospective vulnerability factor for mental disorder and indicate high psychoticism to be a potential risk factor for mood and anxiety disorders. These associations are not confounded by intelligence.
Entities:
Keywords:
Intelligence; Mental disorder; Personality; Prospective cohort study
Authors: Bertus F Jeronimus; Roman Kotov; Johan Ormel; Harriëtte Riese; Elisabeth H Bos; Benjamin Hankin; Judith G M Rosmalen; Albertine J Oldehinkel Journal: Clin Psychol Rev Date: 2013-04-29
Authors: Ronald C Kessler; Steven Heeringa; Matthew D Lakoma; Maria Petukhova; Agnes E Rupp; Michael Schoenbaum; Philip S Wang; Alan M Zaslavsky Journal: Am J Psychiatry Date: 2008-05-07 Impact factor: 18.112