Literature DB >> 3338343

The value of tissue mucin changes and CEA content in evaluation of benign colonic adenomas.

H Turani1, E Kessler, B Lurie.   

Abstract

A combined histopathologic, histochemical, and immunohistochemical study of benign colorectal adenomas is presented. Specimens of 39 adenomas were studied by hematoxylin and eosin (HE) stain, alcian blue-periodic acid Schiff (AB-PAS), and high-iron-diamine-alcian blue (HID-AB). Carcinoembryonic antigen (CEA) was demonstrated by peroxidase-antiperoxidase (PAP) technique. Variable amounts of neutral mucin and decreased sulfated acid mucin content, as well as increased CEA content, were found in the dysplastic epithelium of benign colonic adenomas. These changes were not seen in normal colonic mucosa. It is suggested that the above-mentioned methods may represent an aid in the evaluation of malignant potential of benign polyps.

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Year:  1988        PMID： 3338343     DOI： 10.1007/bf02562643

Source DB:  PubMed          Journal:  Dis Colon Rectum        ISSN： 0012-3706            Impact factor:   4.585


  4 in total

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Journal:  Neoplasia       Date:  2002 Mar-Apr       Impact factor: 5.715

2.  A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse.

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Journal:  Nat Neurosci       Date:  2019-03-18       Impact factor: 24.884

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Journal:  Nat Neurosci       Date:  2019-03-11       Impact factor: 24.884

4.  Frequent traces of EBV infection in Hodgkin and non-Hodgkin lymphomas classified as EBV-negative by routine methods: expanding the landscape of EBV-related lymphomas.

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  4 in total

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