Literature DB >> 33375159

Recent Trends in Enzyme Inhibition and Activation in Drug Design.

Athina Geronikaki1.   

Abstract

It is known that enzymes are involved in many pathological conditions, such as inflammation, diabetes, microbial infections, HIV, neoplastic, neglected diseases and others [...].

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Year:  2020        PMID： 33375159      PMCID： PMC7792938          DOI： 10.3390/molecules26010017

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  21 in total

Review 1.  Strategies to Optimize the Efficacy of Anthelmintic Drugs in Ruminants.

Authors:  Carlos Lanusse; Candela Canton; Guillermo Virkel; Luis Alvarez; Livio Costa-Junior; Adrian Lifschitz
Journal:  Trends Parasitol       Date:  2018-06-27

Review 2.  Inside Perspective of the Synthetic and Computational Toolbox of JAK Inhibitors: Recent Updates.

Authors:  Adriana Coricello; Francesco Mesiti; Antonio Lupia; Annalisa Maruca; Stefano Alcaro
Journal:  Molecules       Date:  2020-07-22       Impact factor: 4.411

3.  Discovery of Novel Tankyrase Inhibitors through Molecular Docking-Based Virtual Screening and Molecular Dynamics Simulation Studies.

Authors:  Vladimir P Berishvili; Alexander N Kuimov; Andrew E Voronkov; Eugene V Radchenko; Pradeep Kumar; Yahya E Choonara; Viness Pillay; Ahmed Kamal; Vladimir A Palyulin
Journal:  Molecules       Date:  2020-07-11       Impact factor: 4.411

4.  Design and Selection of Novel C1s Inhibitors by In Silico and In Vitro Approaches.

Authors:  Katalin Szilágyi; István Hajdú; Beáta Flachner; Zsolt Lőrincz; Júlia Balczer; Péter Gál; Péter Závodszky; Chiara Pirli; Balázs Balogh; István M Mándity; Sándor Cseh; György Dormán
Journal:  Molecules       Date:  2019-10-09       Impact factor: 4.411

5.  Prediction of Severity of Drug-Drug Interactions Caused by Enzyme Inhibition and Activation.

Authors:  Alexander Dmitriev; Dmitry Filimonov; Alexey Lagunin; Dmitry Karasev; Pavel Pogodin; Anastasiya Rudik; Vladimir Poroikov
Journal:  Molecules       Date:  2019-10-31       Impact factor: 4.411

6.  Novel Hit Compounds as Putative Antifungals: The Case of Aspergillus fumigatus.

Authors:  Eftichia Kritsi; Minos-Timotheos Matsoukas; Constantinos Potamitis; Anastasia Detsi; Marija Ivanov; Marina Sokovic; Panagiotis Zoumpoulakis
Journal:  Molecules       Date:  2019-10-25       Impact factor: 4.411

7.  (Q)SAR Models of HIV-1 Protein Inhibition by Drug-Like Compounds.

Authors:  Leonid A Stolbov; Dmitry S Druzhilovskiy; Dmitry A Filimonov; Marc C Nicklaus; Vladimir V Poroikov
Journal:  Molecules       Date:  2019-12-25       Impact factor: 4.411

8.  Data and Text Mining Help Identify Key Proteins Involved in the Molecular Mechanisms Shared by SARS-CoV-2 and HIV-1.

Authors:  Olga Tarasova; Sergey Ivanov; Dmitry A Filimonov; Vladimir Poroikov
Journal:  Molecules       Date:  2020-06-26       Impact factor: 4.411

9.  In Silico Evaluation of the Effectivity of Approved Protease Inhibitors against the Main Protease of the Novel SARS-CoV-2 Virus.

Authors:  Phaedra Eleftheriou; Dionysia Amanatidou; Anthi Petrou; Athina Geronikaki
Journal:  Molecules       Date:  2020-05-29       Impact factor: 4.411

10.  1,2,4-Triazolo[1,5-a]pyrimidines as a Novel Class of Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Activity.

Authors:  Jenny Desantis; Serena Massari; Angela Corona; Andrea Astolfi; Stefano Sabatini; Giuseppe Manfroni; Deborah Palazzotti; Violetta Cecchetti; Christophe Pannecouque; Enzo Tramontano; Oriana Tabarrini
Journal:  Molecules       Date:  2020-03-05       Impact factor: 4.411
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