OBJECTIVE: We intend to identify some probable risk factors that are responsible for the severity of COVID-19 using a meta-analysis. METHODS: The literature exploration lasted up to 18 April 2020 and through PubMed, Google Scholar, EMBASE and Cochrane Library we have identified 10 pertinent publications. To paraphrase the outcomes of autonomous researches, we have performed a random-effect meta-analysis. RESULTS: A total of 2272 patients' information was extracted from the selected literature. We have found gender (male) (Risk ratio [RR] = 1.29, 95% Confidence Interval [CI] 1.07 to 1.54), hypertension (RR = 1.79, 95% CI 1.57 to 2.04), diabetes (RR = 1.57, 95% CI 1.25 to 1.98), fatigue or myalgia (RR = 1.17, 95% CI 1.02 to 1.35), and smoking history (RR = 1.71, 95% CI 1.25 to 2.35) are potential risk factors for the severity of COVID-19. We found fever (RR = 1.21, 95% CI 0.66 to 2.22), cough (1.13, 95% CI 0.98 to 1.30) and diarrhoea (RR = 1.14, 95% CI 0.93 to 1.40) as insignificant risk factors for COVID-19 severity. CONCLUSIONS: The findings of this research may be beneficial to identify patients with higher risks to provide additional medical attention from the very beginning of the treatment.
OBJECTIVE: We intend to identify some probable risk factors that are responsible for the severity of COVID-19 using a meta-analysis. METHODS: The literature exploration lasted up to 18 April 2020 and through PubMed, Google Scholar, EMBASE and Cochrane Library we have identified 10 pertinent publications. To paraphrase the outcomes of autonomous researches, we have performed a random-effect meta-analysis. RESULTS: A total of 2272 patients' information was extracted from the selected literature. We have found gender (male) (Risk ratio [RR] = 1.29, 95% Confidence Interval [CI] 1.07 to 1.54), hypertension (RR = 1.79, 95% CI 1.57 to 2.04), diabetes (RR = 1.57, 95% CI 1.25 to 1.98), fatigue or myalgia (RR = 1.17, 95% CI 1.02 to 1.35), and smoking history (RR = 1.71, 95% CI 1.25 to 2.35) are potential risk factors for the severity of COVID-19. We found fever (RR = 1.21, 95% CI 0.66 to 2.22), cough (1.13, 95% CI 0.98 to 1.30) and diarrhoea (RR = 1.14, 95% CI 0.93 to 1.40) as insignificant risk factors for COVID-19 severity. CONCLUSIONS: The findings of this research may be beneficial to identify patients with higher risks to provide additional medical attention from the very beginning of the treatment.
Authors: Marina Treskova-Schwarzbach; Laura Haas; Sarah Reda; Antonia Pilic; Anna Borodova; Kasra Karimi; Judith Koch; Teresa Nygren; Stefan Scholz; Viktoria Schönfeld; Sabine Vygen-Bonnet; Ole Wichmann; Thomas Harder Journal: BMC Med Date: 2021-08-27 Impact factor: 8.775
Authors: Nina N Kleineberg; Samuel Knauss; Eileen Gülke; Hans O Pinnschmidt; Carolin E M Jakob; Paul Lingor; Kerstin Hellwig; Achim Berthele; Günter Höglinger; Gereon R Fink; Matthias Endres; Christian Gerloff; Christine Klein; Melanie Stecher; Annika Y Classen; Siegbert Rieg; Stefan Borgmann; Frank Hanses; Maria M Rüthrich; Martin Hower; Lukas Tometten; Martina Haselberger; Christiane Piepel; Uta Merle; Sebastian Dolff; Christian Degenhardt; Björn-Erik O Jensen; Maria J G T Vehreschild; Johanna Erber; Christiana Franke; Clemens Warnke Journal: Eur J Neurol Date: 2021-09-03 Impact factor: 6.288
Authors: Jonás Carmona-Pírez; Ignatios Ioakeim-Skoufa; Antonio Gimeno-Miguel; Beatriz Poblador-Plou; Francisca González-Rubio; Dolores Muñoyerro-Muñiz; Juliana Rodríguez-Herrera; Juan Antonio Goicoechea-Salazar; Alexandra Prados-Torres; Román Villegas-Portero Journal: Int J Environ Res Public Health Date: 2022-03-23 Impact factor: 3.390