Literature DB >> 33372214

Impact of Frailty on Outcomes Following Spine Surgery: A Prospective Cohort Analysis of 668 Patients.

Nitin Agarwal1, Ezequiel Goldschmidt1, Tavis Taylor1, Souvik Roy1, Stefanie C Altieri Dunn2, Andrew Bilderback2, Robert M Friedlander1, Adam S Kanter1, David O Okonkwo1, Peter C Gerszten1, D Kojo Hamilton1, Daniel E Hall2,3,4.   

Abstract

BACKGROUND: With an aging population, elderly patients with multiple comorbidities are more frequently undergoing spine surgery and may be at increased risk for complications. Objective measurement of frailty may predict the incidence of postoperative adverse events.
OBJECTIVE: To investigate the associations between preoperative frailty and postoperative spine surgery outcomes including mortality, length of stay, readmission, surgical site infection, and venous thromboembolic disease.
METHODS: As part of a system-wide quality improvement initiative, frailty assessment was added to the routine assessment of patients considering spine surgery beginning in July 2016. Frailty was assessed with the Risk Analysis Index (RAI), and patients were categorized as nonfrail (RAI 0-29) or prefrail/frail (RAI ≥ 30). Comparisons between nonfrail and prefrail/frail patients were analyzed using Fisher's exact test for categorical data or by Wilcoxon rank sum tests for continuous data.
RESULTS: From August 2016 through September 2018, 668 patients (age of 59.5 ± 13.3 yr) had a preoperative RAI score recorded and underwent scheduled spine surgery. Prefrail and frail patients suffered comparatively higher rates of mortality at 90 d (1.9% vs 0.2%, P < .05) and 1 yr (5.1% vs 1.2%, P < .01) from the procedure date. They also had longer in-hospital length of stay (LOS) (3.9 d ± 3.6 vs 3.1 d ± 2.8, P < .001) and higher rates of 60 d (14.6% vs 8.2%, P < .05) and 90 d (15.8% vs 9.8%, P < .05) readmissions.
CONCLUSION: Preoperative frailty, as measured by the RAI, was associated with an increased risk of readmission and 90-d and 1-yr mortality following spine surgery. The RAI can be used to stratify spine patients and inform preoperative surgical decision making.
Copyright © 2020 by the Congress of Neurological Surgeons.

Entities:  

Keywords:  Frailty; Outcomes; Risk Analysis Index; Spine surgery

Mesh:

Year:  2021        PMID: 33372214     DOI: 10.1093/neuros/nyaa468

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  2 in total

1.  Cost analysis comparison between anterior and posterior cervical spine approaches.

Authors:  Alvin Y Chan; Alexander S Himstead; Elliot H Choi; Zachary Hsu; Joshua S Kurtz; Chenyi Yang; Yu-Po Lee; Nitin N Bhatia; Chad T Lefteris; William C Wilson; Frank P K Hsu; Michael Y Oh
Journal:  Surg Neurol Int       Date:  2022-07-15

2.  The Impact of Frailty on Perioperative Outcomes in Patients Receiving Short-Level Posterior Lumbar Interbody Fusion: A Stepwise Propensity Score Matching Analysis.

Authors:  Peng Cui; Peng Wang; Jialin Wang; Xu Liu; Chao Kong; Shibao Lu
Journal:  Clin Interv Aging       Date:  2022-08-25       Impact factor: 3.829

  2 in total

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