Literature DB >> 33370132

Psychiatric outcomes following severe deprivation in early childhood: Follow-up of a randomized controlled trial at age 16.

Kathryn L Humphreys1, Katherine L Guyon-Harris2, Florin Tibu3, Mark Wade4, Charles A Nelson5, Nathan A Fox6, Charles H Zeanah2.   

Abstract

OBJECTIVE: Early psychosocial deprivation is associated with increased risk for psychopathology, yet few studies have examined outcomes in adolescents.
METHOD: At baseline (M age 22 months), 136 children from Bucharest, Romania, living in large institutions, were randomized into foster care (FCG) or to care as usual (CAUG). Caregivers completed psychiatric interviews regarding their children (52 FCG; 51 CAUG) at age 16 years (M = 16.67 years; SD = 0.78) to assess past year diagnoses and symptom counts. In addition, never-institutionalized community comparison children (n = 47) were included.
RESULTS: Ever-institutionalized children had higher rates of meeting criteria for any psychiatric disorder and higher symptom counts of internalizing, externalizing, attention-deficit/hyperactivity, and substance use disorders compared to never-institutionalized children (ps < .05). Using intent-to-treat analyses, we found that children in the CAUG had more than twice the rate of psychiatric disorders than children in the FCG (OR = 2.48, 95% CI [1.12, 5.48]). Furthermore, children in foster care who remained in their original placement did not significantly differ in their rates of psychiatric disorders compared to never-institutionalized children.
CONCLUSIONS: There are many ways children can be separated from parents, including placement into institutional care. The current findings indicate that such placements are associated with significant risks for psychopathology. Moreover, we provide causal evidence for the long-lasting positive effect of foster care in reducing the risk of psychopathology in adolescence, especially among those in stable placements. These results provide strong evidence that early and stable placements into quality foster care may mitigate risk for psychopathology following severe early psychosocial deprivation. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

Entities:  

Mesh:

Year:  2020        PMID: 33370132      PMCID: PMC7909607          DOI: 10.1037/ccp0000613

Source DB:  PubMed          Journal:  J Consult Clin Psychol        ISSN: 0022-006X


  48 in total

1.  Behavioral and emotional symptoms of post-institutionalized children in middle childhood.

Authors:  Kristen L Wiik; Michelle M Loman; Mark J Van Ryzin; Jeffrey M Armstrong; Marilyn J Essex; Seth D Pollak; Megan R Gunnar
Journal:  J Child Psychol Psychiatry       Date:  2011-01       Impact factor: 8.982

2.  NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses.

Authors:  D Shaffer; P Fisher; C P Lucas; M K Dulcan; M E Schwab-Stone
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2000-01       Impact factor: 8.829

3.  Emotional difficulties in early adolescence following severe early deprivation: findings from the English and Romanian adoptees study.

Authors:  Emma Colvert; Michael Rutter; Celia Beckett; Jenny Castle; Christine Groothues; Amanda Hawkins; Jana Kreppner; Thomas G O'connor; Suzanne Stevens; Edmund J S Sonuga-Barke
Journal:  Dev Psychopathol       Date:  2008

Review 4.  Early Adversity and Critical Periods: Neurodevelopmental Consequences of Violating the Expectable Environment.

Authors:  Charles A Nelson; Laurel J Gabard-Durnam
Journal:  Trends Neurosci       Date:  2020-02-12       Impact factor: 13.837

Review 5.  Future Directions in the Study and Treatment of Parent-Child Separation.

Authors:  Kathryn L Humphreys
Journal:  J Clin Child Adolesc Psychol       Date:  2018-12-17

6.  Stressful Life Events, ADHD Symptoms, and Brain Structure in Early Adolescence.

Authors:  Kathryn L Humphreys; Emily L Watts; Emily L Dennis; Lucy S King; Paul M Thompson; Ian H Gotlib
Journal:  J Abnorm Child Psychol       Date:  2019-03

Review 7.  A new model of foster care for young children: the Bucharest early intervention project.

Authors:  Anna T Smyke; Charles H Zeanah; Nathan A Fox; Charles A Nelson
Journal:  Child Adolesc Psychiatr Clin N Am       Date:  2009-07

8.  Designing research to study the effects of institutionalization on brain and behavioral development: the Bucharest Early Intervention Project.

Authors:  Charles H Zeanah; Charles A Nelson; Nathan A Fox; Anna T Smyke; Peter Marshall; Susan W Parker; Sebastian Koga
Journal:  Dev Psychopathol       Date:  2003

9.  Why does early childhood deprivation increase the risk for depression and anxiety in adulthood? A developmental cascade model.

Authors:  Dennis Golm; Barbara Maughan; Edward D Barker; Jonathan Hill; Mark Kennedy; Nicky Knights; Jana Kreppner; Robert Kumsta; Wolff Schlotz; Michael Rutter; Edmund J S Sonuga-Barke
Journal:  J Child Psychol Psychiatry       Date:  2020-02-06       Impact factor: 8.982

10.  Psychosocial deprivation, executive functions, and the emergence of socio-emotional behavior problems.

Authors:  Jennifer Martin McDermott; Sonya Troller-Renfree; Ross Vanderwert; Charles A Nelson; Charles H Zeanah; Nathan A Fox
Journal:  Front Hum Neurosci       Date:  2013-05-10       Impact factor: 3.169

View more
  5 in total

1.  The Bucharest Early Intervention Project: Adolescent mental health and adaptation following early deprivation.

Authors:  Mark Wade; Jill Parsons; Kathryn L Humphreys; Katie A McLaughlin; Margaret A Sheridan; Charles H Zeanah; Charles A Nelson; Nathan A Fox
Journal:  Child Dev Perspect       Date:  2022-07-13

2.  Internet-Based Prevention Program of Victimization for Youth in Care and Care Leavers (EMPOWER YOUTH): Protocol for a Randomized Controlled Trial.

Authors:  Birgit Wagner; Laurence Reuter; Betteke Maria van Noort
Journal:  JMIR Res Protoc       Date:  2022-06-14

3.  Children's Attention and Self-Regulatory Behavior Before and During the COVID-19 Pandemic.

Authors:  Radhika S Raghunathan; Rashelle J Musci; Kristin M Voegtline; Tracey Chambers Thomas; Sara B Johnson
Journal:  J Dev Behav Pediatr       Date:  2021-10-11       Impact factor: 2.988

Review 4.  The effects of early life adversity on children's mental health and cognitive functioning.

Authors:  Mark Wade; Liam Wright; Katherine E Finegold
Journal:  Transl Psychiatry       Date:  2022-06-10       Impact factor: 7.989

Review 5.  The impact of the environment on neurodevelopmental disorders in early childhood.

Authors:  Mônica Ayres de Araújo Scattolin; Rosa Miranda Resegue; Maria Conceição do Rosário
Journal:  J Pediatr (Rio J)       Date:  2021-12-13       Impact factor: 2.990

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.