Literature DB >> 33367577

Emergence and Recovery of Ceftazidime-avibactam Resistance in blaKPC-33-Harboring Klebsiella pneumoniae Sequence Type 11 Isolates in China.

Qingyu Shi1,2, Dandan Yin1,2, Renru Han1,2, Yan Guo1,2, Yonggui Zheng1,2, Shi Wu1,2, Yang Yang1,2, Shirong Li3, Rong Zhang4, Fupin Hu1,2.   

Abstract

This is the first report of ceftazidime-avibactam resistance caused by the blaKPC-33 mutation through the D179Y variant during the treatment of blaKPC-2-positive Klebsiella pneumoniae-related infections in China. The blaKPC-33-containing K. pneumoniae was susceptible to meropenem-vaborbactam, cefepime-zidebactam, tigecycline, and polymyxin B. The blaKPC-33 gene was located on a 77 551-bp transformable plasmid harboring qnrS1 and blaLAP-2. Detecting blaKPC-33-positive K. pneumoniae clinical strains is important for infection control.
© The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

Entities:  

Keywords:  zzm321990 blazzm321990 KPC-2zzm321990 ; zzm321990 blazzm321990 KPC-33zzm321990 ; Carbapenem-resistant K. pneumoniae; Ceftazidime-avibactam; Meropenem-vaborbactam

Year:  2020        PMID： 33367577     DOI： 10.1093/cid/ciaa1521

Source DB:  PubMed          Journal:  Clin Infect Dis        ISSN： 1058-4838            Impact factor:   9.079


  13 in total

1.  Identification of a Novel Ceftazidime-Avibactam-Resistant KPC-2 Variant, KPC-123, in Citrobacter koseri Following Ceftazidime-Avibactam Treatment.

Authors:  Lin Wang; Weiyi Shen; Rong Zhang; Jiachang Cai
Journal:  Front Microbiol       Date:  2022-06-20       Impact factor: 6.064

2.  Effectiveness of a double-carbapenem combinations against carbapenem-resistant Gram-negative bacteria.

Authors:  Jiayue Lu; Yan Qing; Ning Dong; Congcong Liu; Yu Zeng; Qiaoling Sun; Qiao Shentu; Lixing Huang; Yingqian Wu; Hongwei Zhou; Zhangqi Shen; Rong Zhang
Journal:  Saudi Pharm J       Date:  2022-03-14       Impact factor: 4.562

3.  Multiple Novel Ceftazidime-Avibactam-Resistant Variants of blaKPC-2-Positive Klebsiella pneumoniae in Two Patients.

Authors:  Qingyu Shi; Renru Han; Yan Guo; Yang Yang; Shi Wu; Li Ding; Rong Zhang; Dandan Yin; Fupin Hu
Journal:  Microbiol Spectr       Date:  2022-05-19

4.  The Rapid Emergence of Ceftazidime-Avibactam Resistance Mediated by KPC Variants in Carbapenem-Resistant Klebsiella pneumoniae in Zhejiang Province, China.

Authors:  Congcong Liu; Yuchen Wu; Ling Huang; Yanyan Zhang; Qiaoling Sun; Jiayue Lu; Yu Zeng; Ning Dong; Chang Cai; Zhangqi Shen; Gongxiang Chen; Rong Zhang
Journal:  Antibiotics (Basel)       Date:  2022-05-30

5.  Ceftazidime-Avibactam Resistance in Klebsiella pneumoniae Sequence Type 11 Due to a Mutation in Plasmid-Borne bla kpc-2 to bla kpc-33, in Henan, China.

Authors:  Debao Li; Keyang Li; Hongliang Dong; Dongmei Ren; Dandan Gong; Fuguo Jiang; Chunhua Shi; Junmin Li; Qi Zhang; Wenjuan Yan; Yi Li
Journal:  Infect Drug Resist       Date:  2021-05-10       Impact factor: 4.003

6.  Evaluation of the Immunochromatographic NG-Test Carba 5, RESIST-5 O.O.K.N.V., and IMP K-SeT for Rapid Detection of KPC-, NDM-, IMP-, VIM-type, and OXA-48-like Carbapenemase Among Enterobacterales.

Authors:  Renru Han; Yan Guo; Mingjia Peng; Qingyu Shi; Shi Wu; Yang Yang; Yonggui Zheng; Dandan Yin; Fupin Hu
Journal:  Front Microbiol       Date:  2021-01-15       Impact factor: 5.640

7.  Emergence of a KPC-90 Variant that Confers Resistance to Ceftazidime-Avibactam in an ST463 Carbapenem-Resistant Pseudomonas aeruginosa Strain.

Authors:  Yuexing Tu; Dairong Wang; Yiwei Zhu; Jiayan Li; Yan Jiang; Wenhao Wu; Xi Li; Hua Zhou
Journal:  Microbiol Spectr       Date:  2022-01-12

8.  Comparison of Four Carbapenemase Detection Methods for blaKPC-2 Variants.

Authors:  Li Ding; Qingyu Shi; Renru Han; Dandan Yin; Shi Wu; Yang Yang; Yan Guo; Demei Zhu; Fupin Hu
Journal:  Microbiol Spectr       Date:  2021-12-22

9.  Molecular Mechanisms Driving the In Vivo Development of KPC-71-Mediated Resistance to Ceftazidime-Avibactam during Treatment of Carbapenem-Resistant Klebsiella pneumoniae Infections.

Authors:  Xi Li; Huanhuan Ke; Wenhao Wu; Yuexing Tu; Hua Zhou; Yunsong Yu
Journal:  mSphere       Date:  2021-12-22       Impact factor: 4.389

10.  The Genomic Characterization of KPC-Producing Klebsiella pneumoniae from the ICU of a Teaching Hospital in Shanghai, China.

Authors:  Yingying Du; Shikui Mu; Yan Liu; Yinghua Yuan; Yunlou Zhu; Lijie Ma; Qixing Wang; Zhengfang Zhu; Yuhao Liu; Sheng Wang
Journal:  Infect Drug Resist       Date:  2022-01-11       Impact factor: 4.003
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