Literature DB >> 33367439

A near-infrared fluorescent probe based on a hemicyanine dye with an oxazolidine switch for mitochondrial pH detection.

Wafa Mazi1, Yunnan Yan, Yibin Zhang, Shuai Xia, Shulin Wan, Momoko Tajiri, Rudy L Luck, Haiying Liu.   

Abstract

A near-infrared fluorescent probe (AH+) has been prepared by incorporating an oxazolidine switch into a near-infrared hemicyanine dye. The probe shows fast and sensitive responses to pH from an oxazolidine switch to the hemicyanine dye upon pH decreases from 10.0 to 5.0. The probe shows good photostability, low cytotoxicity, and reversible fluorescence responses to pH changes with a pKa value of 7.6. It has been successfully used to determine pH changes in mitochondria.

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Year:  2021        PMID： 33367439      PMCID： PMC7855747          DOI： 10.1039/d0tb02181d

Source DB:  PubMed          Journal:  J Mater Chem B        ISSN： 2050-750X            Impact factor:   6.331


  28 in total

1.  Fluorescent probes with high pKa values based on traditional, near-infrared rhodamine, and hemicyanine fluorophores for sensitive detection of lysosomal pH variations.

Authors:  Wafa Mazi; Rashmi Adhikari; Yibin Zhang; Shuai Xia; Mingxi Fang; Rudy L Luck; Momoko Tajiri; Ashutosh Tiwari; Marina Tanasova; Haiying Liu
Journal:  Methods       Date:  2019-07-22       Impact factor: 3.608

2.  Localization of mitochondria in living cells with rhodamine 123.

Authors:  L V Johnson; M L Walsh; L B Chen
Journal:  Proc Natl Acad Sci U S A       Date:  1980-02       Impact factor: 11.205

3.  Divergent Synthesis of Dihydroxanthene-Hemicyanine Fused Near-Infrared Fluorophores through the Late-Stage Amination of a Bifunctional Precursor.

Authors:  Michelle Jui Hsien Ong; Rajavel Srinivasan; Anthony Romieu; Jean-Alexandre Richard
Journal:  Org Lett       Date:  2016-09-20       Impact factor: 6.005

4.  Near-Infrared Hybrid Rhodol Dyes with Spiropyran Switches for Sensitive Ratiometric Sensing of pH Changes in Mitochondria and Drosophila melanogaster First-Instar Larvae.

Authors:  Yibin Zhang; Shuai Xia; Logan Mikesell; Nick Whisman; Mingxi Fang; Tessa E Steenwinkel; Kai Chen; Rudy L Luck; Thomas Werner; Haiying Liu
Journal:  ACS Appl Bio Mater       Date:  2019-09-27

5.  Development of unique xanthene-cyanine fused near-infrared fluorescent fluorophores with superior chemical stability for biological fluorescence imaging.

Authors:  Hua Chen; Weiying Lin; Haijun Cui; Wenqing Jiang
Journal:  Chemistry       Date:  2014-11-11       Impact factor: 5.236

6.  Near-Infrared Probe Based on Rhodamine Derivative for Highly Sensitive and Selective Lysosomal pH Tracking.

Authors:  Guangle Niu; Panpan Zhang; Weimin Liu; Mengqi Wang; Hongyan Zhang; Jiasheng Wu; Liping Zhang; Pengfei Wang
Journal:  Anal Chem       Date:  2017-01-13       Impact factor: 6.986

7.  A Cyanine Dye to Probe Mitophagy: Simultaneous Detection of Mitochondria and Autolysosomes in Live Cells.

Authors:  Ying Liu; Jin Zhou; Linlin Wang; Xiaoxiao Hu; Xiangjun Liu; Meirong Liu; Zehui Cao; Dihua Shangguan; Weihong Tan
Journal:  J Am Chem Soc       Date:  2016-09-13       Impact factor: 15.419

8.  A cyanine-based fluorescent cassette with aggregation-induced emission for sensitive detection of pH changes in live cells.

Authors:  Mingxi Fang; Shuai Xia; Jianheng Bi; Travis P Wigstrom; Loredana Valenzano; Jianbo Wang; Wafa Mazi; Marina Tanasova; Fen-Tair Luo; Haiying Liu
Journal:  Chem Commun (Camb)       Date:  2018-01-25       Impact factor: 6.222

Review 9.  Mitochondrial drug delivery systems for macromolecule and their therapeutic application to mitochondrial diseases.

Authors:  Yuma Yamada; Hideyoshi Harashima
Journal:  Adv Drug Deliv Rev       Date:  2008-07-04       Impact factor: 15.470

10.  A Near-Infrared Fluorescent Probe Based on a FRET Rhodamine Donor Linked to a Cyanine Acceptor for Sensitive Detection of Intracellular pH Alternations.

Authors:  Yibin Zhang; Jianheng Bi; Shuai Xia; Wafa Mazi; Shulin Wan; Logan Mikesell; Rudy L Luck; Haiying Liu
Journal:  Molecules       Date:  2018-10-18       Impact factor: 4.411
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  3 in total

1.  Rewritable acidochromic papers based on oxazolidine for anticounterfeiting and photosensing of polarity and pH of aqueous media.

Authors:  Bahareh Razavi; Hossein Roghani-Mamaqani; Mehdi Salami-Kalajahi
Journal:  Sci Rep       Date:  2022-06-07       Impact factor: 4.996

2.  A ratiometric near-infrared fluorescent probe based on a novel reactive cyanine platform for mitochondrial pH detection.

Authors:  Shulin Wan; Shuai Xia; Jerry Medford; Emma Durocher; Tessa E Steenwinkel; Lexi Rule; Yibin Zhang; Rudy L Luck; Thomas Werner; Haiying Liu
Journal:  J Mater Chem B       Date:  2021-06-16       Impact factor: 7.571

3.  Development of highly sensitive metal-ion chemosensor and key-lock anticounterfeiting technology based on oxazolidine.

Authors:  Bahareh Razavi; Hossein Roghani-Mamaqani; Mehdi Salami-Kalajahi
Journal:  Sci Rep       Date:  2022-01-20       Impact factor: 4.379
  3 in total

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