Literature DB >> 33363179

Prevalence of and Risk Factors for Community-Based Osteoporosis and Associated Fractures in Beijing: Study Protocol for a Cross-Sectional and Prospective Study.

Menghua Sun1, Yili Zhang2, Hao Shen3, Kai Sun4, Baoyu Qi4, Chenchen Yu4, Yingjie Zhi1, Ranxing Zhang4, Junjie Jiang1, Yan Chai5, Xu Wei4, Yanming Xie1.   

Abstract

Background: Osteoporosis (OP) patients are usually asymptomatic until osteoporotic fractures occur, which makes early diagnosis and prevention difficult, and the associated fractures secondary to OP could be preventable with appropriate management. Therefore, early identification and relevant evidence-based management of OP could guide the prevention of subsequent fractures. This study will investigate the prevalence of OP and the incidence of osteoporotic fractures in Beijing community residents to further explore the related risk factors and put forward suggestions for people aged 45-80 years old.
Methods: Over 2 years, this study will conduct an OP screening and a prospective follow-up in the Beijing community to investigate the incidence of osteoporotic fractures. The study will undertake bone mineral density detection, collect biological samples, and record information via questionnaires. Discussion: The study aims to investigate the potential risk factors for osteoporosis and explore syndromes from traditional Chinese medicine that are associated with this condition based on large samples from the Beijing community. Data on the incidence of osteoporotic fractures among community dwellers in Beijing over the two-years will be available on the Chinese clinical trial registry: ChiCTR-SOC-17013090.
Copyright © 2020 Sun, Zhang, Shen, Sun, Qi, Yu, Zhi, Zhang, Jiang, Chai, Wei and Xie.

Entities:  

Keywords:  Chinese medicine; cross-sectional study; follow-up; osteoporosis; osteoporotic fracture

Year:  2020        PMID: 33363179      PMCID: PMC7757753          DOI: 10.3389/fmed.2020.544697

Source DB:  PubMed          Journal:  Front Med (Lausanne)        ISSN: 2296-858X


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