Literature DB >> 33363130

Polysaccharide-Based Nanomaterials for Ocular Drug Delivery: A Perspective.

Haozhe Yu1,2, Wenyu Wu2, Xiang Lin3, Yun Feng1,2.   

Abstract

Ocular drug delivery is one of the most challenging issues in ophthalmology because of the complex physiological structure of the eye. Polysaccharide-based nanomaterials have been extensively investigated in recent years as ideal carriers for enhancing the bioavailability of drugs in the ocular system because of their biocompatibility and drug solubilization. From this perspective, we discuss the structural instability of polysaccharides and its impact on the synthesis process; examine the potential for developing bioactive polysaccharide-based ocular drug nanocarriers; propose four strategies for designing novel drug delivery nanomaterials; and suggest reviewing the behavior of nanomaterials in ocular tissues.
Copyright © 2020 Yu, Wu, Lin and Feng.

Entities:  

Keywords:  nano; nanocarriers; ocular drug delivery; polysaccharide-based nanomaterials; polysaccharides

Year:  2020        PMID： 33363130      PMCID： PMC7758246          DOI： 10.3389/fbioe.2020.601246

Source DB:  PubMed          Journal:  Front Bioeng Biotechnol        ISSN： 2296-4185


  83 in total

1.  Chitosan-g-poly(N-isopropylacrylamide) copolymers as delivery carriers for intracameral pilocarpine administration.

Authors:  Jui-Yang Lai; Li-Jyuan Luo
Journal:  Eur J Pharm Biopharm       Date:  2017-01-11       Impact factor: 5.571

2.  Bevacizumab-Conjugated Quantum Dots: In Vitro Antiangiogenic Potential and Biosafety in Rat Retina.

Authors:  Cleildo P Santana; Alexandra A P Mansur; Herman S Mansur; Armando da Silva-Cunha
Journal:  J Ocul Pharmacol Ther       Date:  2020-06-09       Impact factor: 2.671

3.  Lycium barbarum polysaccharide extracts preserve retinal function and attenuate inner retinal neuronal damage in a mouse model of transient retinal ischaemia.

Authors:  Di Yang; Kwok-Fai So; Amy Cy Lo
Journal:  Clin Exp Ophthalmol       Date:  2017-04-27       Impact factor: 4.207

4.  Stability issues and approaches to stabilised nanoparticles based drug delivery system.

Authors:  Shaheen Sultana; Nada Alzahrani; Reem Alzahrani; Wejdan Alshamrani; Waad Aloufi; Amena Ali; Shehla Najib; Nasir Ali Siddiqui
Journal:  J Drug Target       Date:  2020-03-19       Impact factor: 5.121

5.  Structural Heteropolysaccharide Adhesion to the Glycocalyx of Visceral Mesothelium.

Authors:  Andrew B Servais; Arne Kienzle; Cristian D Valenzuela; Alexandra B Ysasi; Willi L Wagner; Akira Tsuda; Maximilian Ackermann; Steven J Mentzer
Journal:  Tissue Eng Part A       Date:  2017-06-30       Impact factor: 3.845

6.  Novel multi-responsive and sugarcane bagasse cellulose-based nanogels for controllable release of doxorubicin hydrochloride.

Authors:  Yuanfeng Pan; Junren Liu; Kunni Yang; Pingxiong Cai; Huining Xiao
Journal:  Mater Sci Eng C Mater Biol Appl       Date:  2020-08-11       Impact factor: 7.328

7.  Hyaluronic-acid-modified lipid-polymer hybrid nanoparticles as an efficient ocular delivery platform for moxifloxacin hydrochloride.

Authors:  Dan Liu; Yunfei Lian; Qiuyu Fang; Lu Liu; Jundong Zhang; Juan Li
Journal:  Int J Biol Macromol       Date:  2018-05-17       Impact factor: 6.953

8.  Designing Highly Luminescent Cellulose Nanocrystals with Modulated Morphology for Multifunctional Bioimaging Materials.

Authors:  Xue-Meng Fan; Hou-Yong Yu; Duan-Chao Wang; Juming Yao; Haitao Lin; Chun-Xia Tang; Kam Chiu Tam
Journal:  ACS Appl Mater Interfaces       Date:  2019-12-13       Impact factor: 9.229

Review 9.  Global causes of blindness and distance vision impairment 1990-2020: a systematic review and meta-analysis.

Authors:  Seth R Flaxman; Rupert R A Bourne; Serge Resnikoff; Peter Ackland; Tasanee Braithwaite; Maria V Cicinelli; Aditi Das; Jost B Jonas; Jill Keeffe; John H Kempen; Janet Leasher; Hans Limburg; Kovin Naidoo; Konrad Pesudovs; Alex Silvester; Gretchen A Stevens; Nina Tahhan; Tien Y Wong; Hugh R Taylor
Journal:  Lancet Glob Health       Date:  2017-10-11       Impact factor: 26.763

10.  Preparation of the Potential Ocular Inserts by Electrospinning Method to Achieve the Prolong Release Profile of Triamcinolone Acetonide.

Authors:  Shahla Mirzaeei; Kaveh Berenjian; Rasol Khazaei
Journal:  Adv Pharm Bull       Date:  2018-03-18
View more
  1 in total

Review 1.  Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update.

Authors:  Mehrdad Afarid; Shirin Mahmoodi; Roghayyeh Baghban
Journal:  J Nanobiotechnology       Date:  2022-08-02       Impact factor: 9.429
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.