Literature DB >> 3335784

Lack of cross-reaction in antibody-dependent cellular cytotoxicity between human immunodeficiency virus (HIV) and HIV-related West African strains.

K Ljunggren1, F Chiodi, G Biberfeld, E Norrby, M Jondal, E M Fenyö.   

Abstract

Sera from individuals infected with human immunodeficiency virus (HIV) and HIV-related West African viruses can mediate high-titered, virus-specific antibody-dependent cellular cytotoxicity (ADCC) in all stages of infection. No cross-reactive ADCC can be detected between HIV and HIV-related West African strains LAV-2, HTLV-IV, and SBL-6669. Because these two groups of viruses have antigenically distinct envelope glycoproteins, ADCC-mediating antibodies are most likely directed against envelope antigens. For HIV-specific ADCC, this was further confirmed by using sera reacting with HIV envelope but negative for antibodies against viral core antigens.

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Year:  1988        PMID： 3335784

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  6 in total

Review 1.  Cellular and humoral antigenic epitopes in HIV and SIV.

Authors:  D F Nixon; K Broliden; G Ogg; P A Broliden
Journal:  Immunology       Date:  1992-08       Impact factor: 7.397

2.  Activation of NK cells by HIV-specific ADCC antibodies: role for granulocytes in expressing HIV-1 peptide epitopes.

Authors:  Vijaya Madhavi; Marjon Navis; Amy W Chung; Gamze Isitman; Leia H Wren; Robert De Rose; Stephen J Kent; Ivan Stratov
Journal:  Hum Vaccin Immunother       Date:  2013-01-16       Impact factor: 3.452

3.  Activation of NK cells by ADCC antibodies and HIV disease progression.

Authors:  Amy W Chung; Marjon Navis; Gamze Isitman; Leia Wren; Julie Silvers; Janaki Amin; Stephen J Kent; Ivan Stratov
Journal:  J Acquir Immune Defic Syndr       Date:  2011-10-01       Impact factor: 3.731

4.  Biological significance of the antibody response to HIV antigens expressed on the cell surface.

Authors:  J Goudsmit; K Ljunggren; L Smit; M Jondal; E M Fenyö; M Jonda
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

5.  Antibody-dependent cellular cytotoxicity detects type- and strain-specific antigens among human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus SIVmac isolates.

Authors:  K Ljunggren; G Biberfeld; M Jondal; E M Fenyö
Journal:  J Virol       Date:  1989-08       Impact factor: 5.103

6.  Natural and antibody-dependent cytotoxicity in different clinical stages of human immunodeficiency virus type 1 infection.

Authors:  K Ljunggren; A Karlson; E M Fenyö; M Jondal
Journal:  Clin Exp Immunol       Date:  1989-02       Impact factor: 4.330
  6 in total

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