Literature DB >> 33356958

The Vanderbilt O'Brien Kidney Center.

Ambra Pozzi1,2,3, Raymond C Harris1,2,3.   

Abstract

The Vanderbilt O'Brien Kidney Center (VOKC) is one of the eight National Institutes of Health P30-funded centers in the United States. The mission of these core-based centers is to provide technical and conceptual support to enhance and facilitate research in the field of kidney diseases. The goal of the VOKC is to provide support to understand mechanisms and identify potential therapies for acute and chronic kidney disease. The services provided by the VOKC are meant to help the scientific community to have the right support and tools as well as to select the right animal model, statistical analysis, and clinical study design to perform innovative research and translate discoveries into personalized care to prevent, diagnose, and cure kidney disease. To achieve these goals, the VOKC has in place a program to foster collaborative investigation into critical questions of kidney disease, to personalize diagnosis and treatment of kidney disease, and to disseminate information about kidney disease and the benefits of VOKC services and research. The VOKC is complemented by state-of-the-art cores and an education and outreach program whose goals are to provide an educational platform to enhance the study of kidney disease, to publicize information about services available through the VOKC, and to provide information about kidney disease to patients and other interested members of the community. In this review, we highlight the major services and contributions of the VOKC.

Entities:  

Keywords:  O’Brien Center; core services; education; kidney disease; mouse; outreach; pathophysiology; preclinical studies; workshops

Mesh:

Year:  2020        PMID: 33356958      PMCID: PMC7988814          DOI: 10.1152/ajprenal.00452.2020

Source DB:  PubMed          Journal:  Am J Physiol Renal Physiol        ISSN: 1522-1466


  38 in total

1.  Identification of matrix physicochemical properties required for renal epithelial cell tubulogenesis by using synthetic hydrogels.

Authors:  Ricardo Cruz-Acuña; Adriana Mulero-Russe; Amy Y Clark; Roy Zent; Andrés J García
Journal:  J Cell Sci       Date:  2019-10-21       Impact factor: 5.285

2.  Leucine disposal rate for assessment of amino acid metabolism in maintenance hemodialysis patients.

Authors:  Gerald B Denny; Serpil M Deger; Guanhua Chen; Aihua Bian; Feng Sha; Cindy Booker; Jaclyn T Kesler; Sthuthi David; Charles D Ellis; T Alp Ikizler
Journal:  BMC Nutr       Date:  2016-06-03

3.  Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.

Authors:  Sijo Mathew; Riya J Palamuttam; Glenda Mernaugh; Harini Ramalingam; Zhenwei Lu; Ming-Zhi Zhang; Shuta Ishibe; David R Critchley; Reinhard Fässler; Ambra Pozzi; Charles R Sanders; Thomas J Carroll; Roy Zent
Journal:  Development       Date:  2017-10-09       Impact factor: 6.868

4.  Longitudinal assessment of mouse renal injury using high-resolution anatomic and magnetization transfer MR imaging.

Authors:  Feng Wang; Rosie Jiang; Keiko Takahashi; John Gore; Raymond C Harris; Takamune Takahashi; C Chad Quarles
Journal:  Magn Reson Imaging       Date:  2014-08-02       Impact factor: 2.546

5.  Aquaporin 11 insufficiency modulates kidney susceptibility to oxidative stress.

Authors:  Elena N Atochina-Vasserman; Asel Biktasova; Elena Abramova; Dong-Sheng Cheng; Vasiliy V Polosukhin; Harikrishna Tanjore; Saki Takahashi; Hiroko Sonoda; Liberty Foye; Christo Venkov; Sergey V Ryzhov; Sergey Novitskiy; Natalia Shlonimskaya; Masahiro Ikeda; Timothy S Blackwell; William E Lawson; Andrew J Gow; Raymond C Harris; Mikhail M Dikov; Elena E Tchekneva
Journal:  Am J Physiol Renal Physiol       Date:  2013-03-13

6.  Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading.

Authors:  Ralph T Böttcher; Maik Veelders; Pascaline Rombaut; Jan Faix; Marina Theodosiou; Theresa E Stradal; Klemens Rottner; Roy Zent; Franz Herzog; Reinhard Fässler
Journal:  J Cell Biol       Date:  2017-09-14       Impact factor: 10.539

7.  Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients.

Authors:  Anke Dahlmann; Kathrin Dörfelt; Florian Eicher; Peter Linz; Christoph Kopp; Irina Mössinger; Stephan Horn; Beatrix Büschges-Seraphin; Peter Wabel; Matthias Hammon; Alexander Cavallaro; Kai-Uwe Eckardt; Peter Kotanko; Nathan W Levin; Bernd Johannes; Michael Uder; Friedrich C Luft; Dominik N Müller; Jens M Titze
Journal:  Kidney Int       Date:  2014-08-06       Impact factor: 10.612

8.  Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.

Authors:  Ebony M Flowers; Jessica Sudderth; Lauren Zacharias; Glenda Mernaugh; Roy Zent; Ralph J DeBerardinis; Thomas J Carroll
Journal:  Nat Commun       Date:  2018-02-26       Impact factor: 14.919

9.  Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo.

Authors:  Richard T O'Neil; Sunandan Saha; Ruth Ann Veach; Richard C Welch; Lauren E Woodard; Cliona M Rooney; Matthew H Wilson
Journal:  Nat Commun       Date:  2018-04-10       Impact factor: 14.919

10.  Integration Mapping of piggyBac-Mediated CD19 Chimeric Antigen Receptor T Cells Analyzed by Novel Tagmentation-Assisted PCR.

Authors:  Motoharu Hamada; Nobuhiro Nishio; Yusuke Okuno; Satoshi Suzuki; Nozomu Kawashima; Hideki Muramatsu; Shoma Tsubota; Matthew H Wilson; Daisuke Morita; Shinsuke Kataoka; Daisuke Ichikawa; Norihiro Murakami; Rieko Taniguchi; Kyogo Suzuki; Daiei Kojima; Yuko Sekiya; Eri Nishikawa; Atsushi Narita; Asahito Hama; Seiji Kojima; Yozo Nakazawa; Yoshiyuki Takahashi
Journal:  EBioMedicine       Date:  2018-08-03       Impact factor: 8.143

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  1 in total

Review 1.  The Michigan O'Brien Kidney Research Center: transforming translational kidney research through systems biology.

Authors:  Markus Bitzer; Wenjun Ju; Lalita Subramanian; Jonathan P Troost; Joseph Tychewicz; Becky Steck; Roger C Wiggins; Debbie S Gipson; Crystal A Gadegbeku; Frank C Brosius; Matthias Kretzler; Subramaniam Pennathur
Journal:  Am J Physiol Renal Physiol       Date:  2022-08-04
  1 in total

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