Wei He1, Zi-Xue Sun2, Guang-Ce Wang1. 1. Department of Urology, the First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan 450000, China. 2. Department of Reproductive Medicine, Henan Provincial Hospital of Traditional Chinese Medicine, Zhengzhou, Henan 450000, China.
Abstract
OBJECTIVE: To evaluate the effect and safety of the magnetic resonance electromagnetic therapy (MREM) combined with Qianlie Beixi Capsules (QBC) in the treatment of chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS). METHODS: Using a prospective, two-center, randomized, open, positive drug-loading, parallel-controlled clinical design, we randomly divided 124 patients with CP/CPPS into a control and an observation group of equal number, the former treated with QBC and the latter with QBC combined with MREM for a course of 14 days. Then, we compared the NIH-CPSI scores before and after treatment, the total effectiveness rate and safety between the two groups of patients. RESULTS: After treatment, the patients in both the observation and control groups showed significantly improved total and specific item scores on NIH-CPSI (P < 0.05), and those of the observation group achieved even more significant improvement than the controls either in the total NIH-CPSI score (16.65 ± 7.90 vs 21.95 ± 5.70, P < 0.05) or in the pain symptom score (7.34 ± 3.26 vs 9.50 ± 2.47, P < 0.05), urination symptom score (3.53 ± 2.56 vs 4.50 ± 2.35, P < 0.05) and quality of life score (5.94 ± 2.89 vs 8.03 ± 2.60, P < 0.05). The total effectiveness rate was remarkably higher in the observation than in the control group (83.87% vs 53.23%, P < 0.05). No adverse events or reactions were observed in either group of the patients during the trial. CONCLUSIONS: Magnetic resonance electromagnetic therapy combined with Qianlie Beixi Capsules can significantly relieve the clinical symptoms of CP/CPPS patients with high effectiveness and safety.
OBJECTIVE: To evaluate the effect and safety of the magnetic resonance electromagnetic therapy (MREM) combined with Qianlie Beixi Capsules (QBC) in the treatment of chronic prostatitis / chronic pelvic pain syndrome (CP/CPPS). METHODS: Using a prospective, two-center, randomized, open, positive drug-loading, parallel-controlled clinical design, we randomly divided 124 patients with CP/CPPS into a control and an observation group of equal number, the former treated with QBC and the latter with QBC combined with MREM for a course of 14 days. Then, we compared the NIH-CPSI scores before and after treatment, the total effectiveness rate and safety between the two groups of patients. RESULTS: After treatment, the patients in both the observation and control groups showed significantly improved total and specific item scores on NIH-CPSI (P < 0.05), and those of the observation group achieved even more significant improvement than the controls either in the total NIH-CPSI score (16.65 ± 7.90 vs 21.95 ± 5.70, P < 0.05) or in the pain symptom score (7.34 ± 3.26 vs 9.50 ± 2.47, P < 0.05), urination symptom score (3.53 ± 2.56 vs 4.50 ± 2.35, P < 0.05) and quality of life score (5.94 ± 2.89 vs 8.03 ± 2.60, P < 0.05). The total effectiveness rate was remarkably higher in the observation than in the control group (83.87% vs 53.23%, P < 0.05). No adverse events or reactions were observed in either group of the patients during the trial. CONCLUSIONS: Magnetic resonance electromagnetic therapy combined with Qianlie Beixi Capsules can significantly relieve the clinical symptoms of CP/CPPS patients with high effectiveness and safety.
Entities:
Keywords:
National Institute of Health Chronic Prostatitis Symptom Index zzm321990zzm321990 ; Qianlie Beixi Capsules; magnetic resonance electromagnetic therapy; chronic prostatitis / chronic pelvic pain syndrome
Authors: Alicia María de Pedro Negri; María Jesús Ruiz Prieto; Esther Díaz-Mohedo; Rocío Martín-Valero Journal: Int J Environ Res Public Health Date: 2022-05-10 Impact factor: 4.614