Literature DB >> 33353254

The Phospholipid Research Center: Current Research in Phospholipids and Their Use in Drug Delivery.

Simon Drescher1, Peter van Hoogevest1.   

Abstract

This review summarizes the research on phospholipids and their use for drug delivery related to the Phospholipid Research Center Heidelberg (PRC). The focus is on projects that have been approved by the PRC since 2017 and are currently still ongoing or have recently been completed. The different projects cover all facets of phospholipid research, from basic to applied research, including the use of phospholipids in different administration forms such as liposomes, mixed micelles, emulsions, and extrudates, up to industrial application-oriented research. These projects also include all routes of administration, namely parenteral, oral, and topical. With this review we would like to highlight possible future research directions, including a short introduction into the world of phospholipids.

Entities:  

Keywords:  drug delivery; lecithin; oral; parenteral; phospholipids; topical

Year:  2020        PMID: 33353254      PMCID: PMC7766331          DOI: 10.3390/pharmaceutics12121235

Source DB:  PubMed          Journal:  Pharmaceutics        ISSN: 1999-4923            Impact factor:   6.321


  9 in total

1.  Influence of Oil Polarity and Cosurfactants on the Foamability of Mono- and Diacylphosphatidylcholine Stabilized Emulsions.

Authors:  Manuel Bunk; Rolf Daniels
Journal:  Pharmaceutics       Date:  2022-06-07       Impact factor: 6.525

Review 2.  Chemotherapeutic effects of Apigenin in breast cancer: Preclinical evidence and molecular mechanisms; enhanced bioavailability by nanoparticles.

Authors:  Moein Adel; Masoumeh Zahmatkeshan; Abolfazl Akbarzadeh; Navid Rabiee; Sepideh Ahmadi; Peyman Keyhanvar; Seyed Mahdi Rezayat; Alexander Marcus Seifalian
Journal:  Biotechnol Rep (Amst)       Date:  2022-04-12

Review 3.  Severe acute respiratory syndrome coronavirus 2 variants-Possibility of universal vaccine design: A review.

Authors:  Eunhye Yoon; Dahyun Kim; Hyeeun Jeon; Yejin Kwon; Yejin Jang; Sulhee Kim; Kwang Yeon Hwang
Journal:  Comput Struct Biotechnol J       Date:  2022-06-23       Impact factor: 6.155

4.  Optimal combination of cationic lipid and phospholipid in cationic liposomes for gene knockdown in breast cancer cells and mouse lung using siRNA lipoplexes.

Authors:  Yoshiyuki Hattori; Min Tang; Satomi Torii; Kana Tomita; Ayane Sagawa; Nodoka Inoue; Reo Yamagishi; Kei-Ichi Ozaki
Journal:  Mol Med Rep       Date:  2022-06-10       Impact factor: 3.423

Review 5.  The nano delivery systems and applications of mRNA.

Authors:  Mingyuan Li; Yuan Li; Shiqin Li; Lin Jia; Haomeng Wang; Meng Li; Jie Deng; Ali Zhu; Liqiao Ma; Weihong Li; Peng Yu; Tao Zhu
Journal:  Eur J Med Chem       Date:  2021-10-08       Impact factor: 6.514

6.  Liposomes as Adjuvants and Vaccine Delivery Systems.

Authors:  D S Tretiakova; E L Vodovozova
Journal:  Biochem (Mosc) Suppl Ser A Membr Cell Biol       Date:  2022-02-14

Review 7.  Microbial Lipases and Their Potential in the Production of Pharmaceutical Building Blocks.

Authors:  César A Godoy; Juan S Pardo-Tamayo; Oveimar Barbosa
Journal:  Int J Mol Sci       Date:  2022-09-01       Impact factor: 6.208

Review 8.  Hyaluronic Acid within Self-Assembling Nanoparticles: Endless Possibilities for Targeted Cancer Therapy.

Authors:  Manuela Curcio; Orazio Vittorio; Jessica Lilian Bell; Francesca Iemma; Fiore Pasquale Nicoletta; Giuseppe Cirillo
Journal:  Nanomaterials (Basel)       Date:  2022-08-18       Impact factor: 5.719

9.  A QbD Approach to Design and to Optimize the Self-Emulsifying Resveratrol-Phospholipid Complex to Enhance Drug Bioavailability through Lymphatic Transport.

Authors:  Syed Abul Layes Gausuzzaman; Mithun Saha; Shahid Jaman Dip; Shaiful Alam; Arup Kumar; Harinarayan Das; Shazid Md Sharker; Md Abdur Rashid; Mohsin Kazi; Hasan Mahmud Reza
Journal:  Polymers (Basel)       Date:  2022-08-08       Impact factor: 4.967

  9 in total

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