| Literature DB >> 33352100 |
Hüseyin Arıkan1, Dilek Karadoğan2, Fatma Tokgöz Akyıl3, Aycan Yüksel4, Zehra Nur Töreyin5, Canan Gündüz Gürkan6, Feride Marim7, Tuğba Şişmanlar Eyüboğlu8, Nagehan Emiralioğlu9, Tuğba Ramaslı Gürsoy8, İrem Şerifoğlu10, Abdulsamet Sandal11, Aslı Öncel12, Berrin Er13, Neslihan Köse14, Dorina Esendağlı15, Mina Hızal16, Aslıhan Banu Er17, Fatma Esra Günaydın18, İlknur Kaya19, Hilal Özakıncı20, Ümran Özden Sertçelik12, Hatice Çelik Tuğlu21, Nilüfer Aylin Acet Özürk18, Özlem Ataoğlu22, Ahu Cerit Çakır23, Hüseyin Toptay24, Merve Erçelik22, Elif Develi25, Selman Çelik26, Fatma Gülsüm Karakaş27, Halime Yıldırım28, Damla Karadeniz Güven12, Nazlı Çetin29, Sümeyye Nur Aslan Küçükyurt30, Mehmet Fatih Elverişli31, Pinar Yıldız Gülhan32, Metin Akgün33.
Abstract
As coronavirus disease 2019 (COVID-19) spreads across the world, the ongoing clinical trials are leading to a big race worldwide to develop a treatment that will help control the pandemic. Unfortunately, COVID-19 does not have any known effective treatment with reliable study results yet. In this pandemic, there is not a lot of time to develop a new specific agent because of the rapid spread of the disease. The process of developing a vaccine is long and requires hard work. Although the pathophysiology of the disease is not fully understood, some of the proposed treatment alternatives are based on old evidence and some have been used with the idea that they might work owing to their mechanism of action. The efficacy, reliability, and safety of the currently available treatment alternatives are therefore a matter of debate. Currently, the main therapies used in the treatment of COVID-19 are antiviral drugs and chloroquine/hydroxychloroquine. Other proposed options include tocilizumab, convalescent plasma, and steroids, but the mainstay of the treatment in intensive care units remains supportive therapies.Entities:
Year: 2020 PMID: 33352100 PMCID: PMC7752114 DOI: 10.5152/TurkThoracJ.2020.20125
Source DB: PubMed Journal: Turk Thorac J ISSN: 2148-7197