| Literature DB >> 33350906 |
Jacqueline K Lim, Mabel Carabali, Tansy Edwards, Ahmed Barro, Jung-Seok Lee, Desire Dahourou, Kang Sung Lee, Teguewende Nikiema, Mee Young Shin, Emmanuel Bonnet, Therese Kagone, Losseni Kaba, Suk Namkung, Paul-André Somé, Jae Seung Yang, Valéry Ridde, In-Kyu Yoon, Neal Alexander, Yaro Seydou.
Abstract
Because of limited data on dengue virus in Burkina Faso, we conducted 4 consecutive age-stratified longitudinal serologic surveys, ≈6 months apart, among persons 1-55 years of age, during June 2015-March 2017, which included a 2016 outbreak. The seroconversion rate before the serosurvey enrollment was estimated by binomial regression, taking age as the duration of exposure, and assuming constant force of infection (FOI) over age and calendar time. We calculated FOI between consecutive surveys and rate ratios for potentially associated characteristics based on seroconversion using the duration of intervals. Among 2,897 persons at enrollment, 66.3% were IgG-positive, and estimated annual FOI was 5.95%. Of 1,269 enrollees participating in all 4 serosurveys, 438 were IgG-negative at enrollment. The annualized FOI ranged from 10% to 20% (during the 2016 outbreak). Overall, we observed high FOI for dengue. These results could support decision-making about control and preventive measures for dengue.Entities:
Keywords: Aedes mosquitoes; Africa; Burkina Faso; IgG; cross reactivity; dengue; flaviviruses; force of infection; outbreaks; population seroprevalence; regression models; seroconversion; viruses
Mesh：
Year: 2021 PMID： 33350906 PMCID： PMC7774580 DOI： 10.3201/eid2701.191650
Source DB: PubMed Journal: Emerg Infect Dis ISSN： 1080-6040 Impact factor: 6.883