Literature DB >> 33350228

[Advances in studies on steroidal alkaloids and their pharmacological activities in genus Veratrum].

Zhang Meng-Zhen1, Gao Li-Juan1, X U Shi-Fang1, Huang Wen-Kang1, L I Xiao-Yu1, Y E Yi-Ping1.   

Abstract

Genus Veratrum plants contain a diversity of steroidal alkaloids, so far at least 184 steroidal alkaloids attributed to cevanine type(A-1~A-69), veratramine type(B-1~B-21), jervanine type(C-1~C-31), solanidine type(D-1~D-10) and verazine type(E-1~E-53), respectively, have been isolated and identified in the genus Veratrum. Their pharmacological activities mainly focused on decreasing blood pressure, anti-platelet aggregation and anti-thrombosis, anti-inflammatory and analgesic, and antitumor effect. This paper classified and summarized the 184 kind of steroidal alkaloids from the Veratrum plants and their major pharmalogical activities in order to provide the scientific basis for the further development and utilization of active alkaloids.

Entities:  

Keywords:  chemical constituents; genus Veratrum; pharmalogical activities; steroidal alkaloids

Year:  2020        PMID: 33350228     DOI: 10.19540/j.cnki.cjcmm.20200612.201

Source DB:  PubMed          Journal:  Zhongguo Zhong Yao Za Zhi        ISSN: 1001-5302


  1 in total

1.  Identification of Veratrum Species in Pimacao Based on ITS2 Sequences and Steroidal Alkaloids by a Pseudo-Targeted Metabolomics Method.

Authors:  Qinwei Lu; Shuaiyao Wang; Zili Yin; Qinsheng Chen; Xingchao He; Qi Wang; Qingyu Hu; Yu Gu; Huiru Tang; Hui Xie
Journal:  Front Plant Sci       Date:  2022-04-11       Impact factor: 6.627

  1 in total

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