Literature DB >> 33349415

Thoracotomy and Pericardiotomy for Access to the Heart in Horses: Surgical Procedure and Effects on Anesthetic Variables.

Ditte Marie Top Adler1, Klaus Hopster2, Charlotte Hopster-Iversen3, Merle Fenner3, Rikke Buhl3, Stine Jacobsen3.   

Abstract

Thoracotomy is an uncommon procedure in horses but remains essential in a variety of cases of pleuropneumonia, pericarditis, thoracic trauma or diaphragmatic herniation, and for experimental thoracic and cardiac procedures. This study aimed at developing an experimental surgical procedure allowing access to the entire circumference of the heart and describing the effect of thoracotomy on pulmonary gas exchange in these horses. The study consisted of two arms, arm one (undergoing thoracotomy), was a terminal experimental study that included 11 Standardbred horses with experimentally induced (by tachypacing) atrial fibrillation. Arm two consisted of 6 Standardbred horses undergoing anesthesia for reasons unrelated to the present study. These horses functioned as controls. Anesthesia was induced using zolazepam and tiletamine. Anesthesia was maintained with isoflurane in 100% oxygen and ventilation with intermittent positive pressure (IPPV); no positive end-expiratory pressure (PEEP) was performed. Rib resection and pericardiotomy were performed for complete exposure of the entire circumference of the heart. Arterial blood samples were collected prior to, 5 and 30 minutes after puncture of pleura parietalis. In 10 horses, resection of the fifth rib was adequate for exposure of the heart. In one horse, removal of the sixth rib was also necessary. The duration of the surgical procedure (thoracotomy, pericardiotomy) was < 45 minutes. During a thoracotomy, PaO2 decreased significantly (P < .05) from 291.8 ± 82.8 mmHg to 165.2 ± 73.5 mmHg but was not different from normal anesthetized controls. The PaCO2 remained within normal limits. This surgical approach provided access to the entire circumference of the heart.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Anesthesia; Gas exchange; Surgery; Thoracotomy; Ventilation

Mesh:

Substances:

Year:  2020        PMID: 33349415     DOI: 10.1016/j.jevs.2020.103315

Source DB:  PubMed          Journal:  J Equine Vet Sci        ISSN: 0737-0806            Impact factor:   1.583


  2 in total

1.  Inhibition of Small-Conductance Calcium-Activated Potassium Current (I K,Ca) Leads to Differential Atrial Electrophysiological Effects in a Horse Model of Persistent Atrial Fibrillation.

Authors:  Merle Friederike Fenner; Giulia Gatta; Stefan Sattler; Marion Kuiper; Eva Melis Hesselkilde; Ditte M T Adler; Morten Smerup; Ulrich Schotten; Ulrik Sørensen; Jonas Goldin Diness; Thomas Jespersen; Sander Verheule; Arne Van Hunnik; Rikke Buhl
Journal:  Front Physiol       Date:  2021-02-09       Impact factor: 4.566

2.  Increased fibroblast accumulation in the equine heart following persistent atrial fibrillation.

Authors:  Arnela Saljic; Merle Friederike Fenner; Joris Winters; Mette Flethøj; Caroline Eggert Eggertsen; Helena Carstensen; Sarah Dalgas Nissen; Eva Melis Hesselkilde; Arne van Hunnik; Ulrich Schotten; Ulrik Sørensen; Thomas Jespersen; Sander Verheule; Rikke Buhl
Journal:  Int J Cardiol Heart Vasc       Date:  2021-07-20
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.