Literature DB >> 33347610

Silent hypoxaemia in COVID-19 patients.

Tatum S Simonson1, Tracy L Baker2, Robert B Banzett3, Tammie Bishop4, Jerome A Dempsey5, Jack L Feldman6, Patrice G Guyenet7, Emma J Hodson8,9, Gordon S Mitchell10, Esteban A Moya1, Brandon T Nokes1, Jeremy E Orr1, Robert L Owens1, Marc Poulin11, Jean M Rawling12, Christopher N Schmickl1, Jyoti J Watters2, Magdy Younes13, Atul Malhotra1.   

Abstract

The clinical presentation of COVID-19 due to infection with SARS-CoV-2 is highly variable with the majority of patients having mild symptoms while others develop severe respiratory failure. The reason for this variability is unclear but is in critical need of investigation. Some COVID-19 patients have been labelled with 'happy hypoxia', in which patient complaints of dyspnoea and observable signs of respiratory distress are reported to be absent. Based on ongoing debate, we highlight key respiratory and neurological components that could underlie variation in the presentation of silent hypoxaemia and define priorities for subsequent investigation.
© 2020 The Authors. The Journal of Physiology © 2020 The Physiological Society.

Entities:  

Keywords:  COVID-19; SARS-CoV-2; dyspnoea; happy hypoxia; silent hypoxaemia

Mesh：

Year:  2021        PMID： 33347610      PMCID： PMC7902403          DOI： 10.1113/JP280769

Source DB:  PubMed          Journal:  J Physiol        ISSN： 0022-3751            Impact factor:   6.228


  73 in total

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Review 9.  The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients.

Authors:  Yan-Chao Li; Wan-Zhu Bai; Tsutomu Hashikawa
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  27 in total

Review 1.  The effect of HIF on metabolism and immunity.

Authors:  Cormac T Taylor; Carsten C Scholz
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Authors:  Elaheh Sajjadi; Yasin B Seven; Jessica G Ehrbar; James P Wymer; Gordon S Mitchell; Barbara K Smith
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3.  Feasibility and accuracy of the 40-steps desaturation test to determine outcomes in a cohort of patients presenting to hospital with and without COVID-19.

Authors:  Gwenllian Haf Rhys; Tara Wakeling; Shakeeb H Moosavi; Jonathan P Moore; Helen Dawes; Matthew Knight; Matt Inada-Kim; Erika F Christensen; Christian P Subbe
Journal:  Clin Med (Lond)       Date:  2022-04-20       Impact factor: 5.410

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Journal:  Influenza Other Respir Viruses       Date:  2021-05-24       Impact factor: 5.606

Review 5.  Relevance of carotid bodies in COVID-19: A hypothetical viewpoint.

Authors:  Benedito H Machado; Julian F R Paton
Journal:  Auton Neurosci       Date:  2021-04-17       Impact factor: 2.355

6.  Clinical and radiological findings of silent hypoxia among COVID-19 patients.

Authors:  Ayako Okuhama; Masahiro Ishikane; Masatoshi Hotta; Lubna Sato; Yutaro Akiyama; Shinichiro Morioka; Setsuko Suzuki; Tsuyoshi Tajima; Makiko Yamamoto; Katsuji Teruya; Shinyu Izumi; Norio Ohmagari
Journal:  J Infect Chemother       Date:  2021-07-08       Impact factor: 2.211

7.  A more holistic view could contribute to our understanding of 'silent hypoxaemia' in Covid-19 patients.

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Journal:  J Physiol       Date:  2021-06-24       Impact factor: 6.228

8.  Standardizing PaO2 for PaCO2 in P/F ratio predicts in-hospital mortality in acute respiratory failure due to Covid-19: A pilot prospective study.

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