| Literature DB >> 3334724 |
M Sakaizumi1, Y Hashimoto, A Suzuki, T Yamakawa, Y Kiuchi, K Moriwaki.
Abstract
The polymorphic variation of liver GM1 (NeuGc) ganglioside was found in inbred strains of the mouse. The genetic analysis using C57BL/10 (GM1-negative) and SWR (GM1-positive) mice revealed that a single autosomal gene (Ggm-1) was involved in the expression of liver GM1(NeuGc) and that C57BL/10 mice lacking GM1(NeuGc) expression carried a defective gene on Ggm-1. Since our previous study on H-2 congenic mice indicated that Ggm-1 was linked to the H-2 complex, in this study we measured recombination frequencies among Ggm-1, Glo-1 and H-2K in the backcross progeny between (C57BL/10 X SWR)F1 and C57BL/10. Ggm-1 was mapped 1 cM centromeric to H-2K on chromosome 17.Entities:
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Year: 1988 PMID： 3334724 DOI： 10.1007/bf00404445
Source DB: PubMed Journal: Immunogenetics ISSN： 0093-7711 Impact factor: 2.846