Literature DB >> 33346928

Membrane protein biogenesis by the EMC.

Sara Alvira1, Robin A Corey2, Ian Collinson1, Karin Römisch3.   

Abstract

The endoplasmic reticulum (ER) membrane protein complex (EMC) was identified over a decade ago in a genetic screen for ER protein homeostasis. The EMC inserts transmembrane domains (TMDs) with limited hydrophobicity. Two recent cryo-EM structures, and a third model based on partial high- and low-resolution structures, suggest how this is accomplished.
© 2020 The Authors.

Entities:  

Mesh：

Substances：

Year:  2020        PMID： 33346928      PMCID： PMC7809699          DOI： 10.15252/embj.2020107407

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  11 in total

1.  Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule.

Authors:  G von Heijne
Journal:  J Mol Biol       Date:  1992-05-20       Impact factor: 5.469

2.  VMD: visual molecular dynamics.

Authors:  W Humphrey; A Dalke; K Schulten
Journal:  J Mol Graph       Date:  1996-02

3.  Structural basis of Sec-independent membrane protein insertion by YidC.

Authors:  Kaoru Kumazaki; Shinobu Chiba; Mizuki Takemoto; Arata Furukawa; Ken-ichi Nishiyama; Yasunori Sugano; Takaharu Mori; Naoshi Dohmae; Kunio Hirata; Yoshiko Nakada-Nakura; Andrés D Maturana; Yoshiki Tanaka; Hiroyuki Mori; Yuji Sugita; Fumio Arisaka; Koreaki Ito; Ryuichiro Ishitani; Tomoya Tsukazaki; Osamu Nureki
Journal:  Nature       Date:  2014-04-16       Impact factor: 49.962

4.  The role of the strictly conserved positively charged residue differs among the Gram-positive, Gram-negative, and chloroplast YidC homologs.

Authors:  Yuanyuan Chen; Raunak Soman; Sri Karthika Shanmugam; Andreas Kuhn; Ross E Dalbey
Journal:  J Biol Chem       Date:  2014-10-30       Impact factor: 5.157

5.  The ubiquitous and ancient ER membrane protein complex (EMC): tether or not?

Authors:  Jeremy G Wideman
Journal:  F1000Res       Date:  2015-08-25

6.  The architecture of EMC reveals a path for membrane protein insertion.

Authors:  John P O'Donnell; Ben P Phillips; Yuichi Yagita; Szymon Juszkiewicz; Armin Wagner; Duccio Malinverni; Robert J Keenan; Elizabeth A Miller; Ramanujan S Hegde
Journal:  Elife       Date:  2020-05-27       Impact factor: 8.140

7.  Structure of the ER membrane complex, a transmembrane-domain insertase.

Authors:  Lin Bai; Qinglong You; Xiang Feng; Amanda Kovach; Huilin Li
Journal:  Nature       Date:  2020-06-03       Impact factor: 49.962

8.  Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages.

Authors:  Elena Rensen; Florian Mueller; Viviana Scoca; Jyotsana J Parmar; Philippe Souque; Christophe Zimmer; Francesca Di Nunzio
Journal:  EMBO J       Date:  2020-12-03       Impact factor: 11.598

9.  Structure and Dynamics of the Central Lipid Pool and Proteins of the Bacterial Holo-Translocon.

Authors:  Remy Martin; Andreas Haahr Larsen; Robin Adam Corey; Søren Roi Midtgaard; Henrich Frielinghaus; Christiane Schaffitzel; Lise Arleth; Ian Collinson
Journal:  Biophys J       Date:  2019-04-09       Impact factor: 4.033

Review 10.  Squaring the EMC - how promoting membrane protein biogenesis impacts cellular functions and organismal homeostasis.

Authors:  Norbert Volkmar; John C Christianson
Journal:  J Cell Sci       Date:  2020-04-24       Impact factor: 5.285
View more
  3 in total

Review 1.  Cryo-EM structures of the endoplasmic reticulum membrane complex.

Authors:  Lin Bai; Huilin Li
Journal:  FEBS J       Date:  2021-03-06       Impact factor: 5.542

2.  The ER membrane complex (EMC) can functionally replace the Oxa1 insertase in mitochondria.

Authors:  Büsra Güngör; Tamara Flohr; Sriram G Garg; Johannes M Herrmann
Journal:  PLoS Biol       Date:  2022-03-01       Impact factor: 8.029

3.  The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei.

Authors:  Advaitha Iyer; Moritz Niemann; Mauro Serricchio; Caroline E Dewar; Silke Oeljeklaus; Luce Farine; Bettina Warscheid; André Schneider; Peter Bütikofer
Journal:  PLoS Pathog       Date:  2022-05-02       Impact factor: 7.464
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.