| Literature DB >> 33346858 |
Pietro Nenoff1, Anke Süß2, Ina Schulze3, Laura Meißner4, Christina Fritsch4, Bettina Schulz4, Silke Hennig4, Michael Borte4, Marlen Zurek4, Gabriele Ginter-Hanselmayer5.
Abstract
Scabies or mange is currently a common dermatosis in Germany and other countries, and should be more important in health policy. It affects a cross-section of society, including all age groups, from infants to the aged. Locals and people with a migration background both suffer from this highly contagious ectoparasite infection with excessive, predominately nocturnal itching. Clinical diagnosis represents a challenge for the experienced dermatologist due to the variety of dermatosis to be considered in the differential diagnosis. It is still unclear whether treatment failure or the recurrences observed everywhere are due to in vitro and in vivo resistance of the pathogen agent Sarcoptes scabiei against permethrin or ivermectin. Therapeutic errors seem to play a role as often not all direct contact persons are recorded and treated with antiscabious treatment. They form the reservoir for reinfections. In the event of repeated nonresponse to topical (permethrin) and/or oral antiscabious treatment, alternative topical preparations-benzyl benzoate or crotamiton-should be used. Combination with ivermectin is mandatory.Entities:
Keywords: Chronic recalcitrant course; Relapse; Resistance; Sarcoptes scabiei varietas hominis; Transmission
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Year: 2021 PMID: 33346858 DOI: 10.1007/s00105-020-04729-6
Source DB: PubMed Journal: Hautarzt ISSN: 0017-8470 Impact factor: 0.751