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Literature DB >> 3334411

Kinetic-effect models and their applications.

Abstract

This article focuses on mathematical models that analyze the time course of drug effects in humans. Any such model, whether parametric or nonparametric, is termed a kinetic-effect model (KEM). These models serve to describe (interpolation) and to predict (extrapolation) the effect-time profile. KEMs are applicable to many problems in pharmaceutics, pharmacology, and clinical pharmacology.

Entities: Species

Mesh：

Year: 1987 PMID： 3334411 DOI： 10.1023/a:1016402616081

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

13 in total

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Journal: Clin Pharmacokinet Date: 1981 Nov-Dec Impact factor: 6.447

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Journal: Clin Pharmacol Ther Date: 1979-03 Impact factor: 6.875

10. Pharmacodynamic models of various beta blockers: an explanation for the long duration of action of bopindolol.

Authors: J Grevel
Journal: J Cardiovasc Pharmacol Date: 1986 Impact factor: 3.105

3 in total

Review 1. Methodological issues in pharmacokinetic-pharmacodynamic modelling.

Authors: E Bellissant; V Sébille; G Paintaud
Journal: Clin Pharmacokinet Date: 1998-08 Impact factor: 6.447

Review 2. Pharmacokinetic-pharmacodynamic relationships in phase I/phase II of drug development.

Authors: A Van Peer; E Snoeck; M L Huang; J Heykants
Journal: Eur J Drug Metab Pharmacokinet Date: 1993 Jan-Mar Impact factor: 2.441

Review 3. Pharmacokinetic-pharmacodynamic relationships for benzodiazepines.

Authors: B E Laurijssens; D J Greenblatt
Journal: Clin Pharmacokinet Date: 1996-01 Impact factor: 6.447

3 in total