Literature DB >> 3334243

Inhibitors of renin as potential therapeutic agents.

J M Wood1, J L Stanton, K G Hofbauer.   

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Year:  1987        PMID： 3334243     DOI： 10.3109/14756368709020115

Source DB:  PubMed          Journal:  J Enzyme Inhib        ISSN： 1026-5457


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  11 in total

1.  Pharmacological investigations of a new renin inhibitor in normal sodium-unrestricted volunteers.

Authors:  M de Gasparo; F Cumin; J Nussberger; T T Guyenne; J M Wood; J Menard
Journal:  Br J Clin Pharmacol       Date:  1989-05       Impact factor: 4.335

Review 2.  Sequence, Structural Analysis and Metrics to Define the Unique Dynamic Features of the Flap Regions Among Aspartic Proteases.

Authors:  Lara McGillewie; Muthusamy Ramesh; Mahmoud E Soliman
Journal:  Protein J       Date:  2017-10       Impact factor: 2.371

3.  Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.

Authors:  Lanqi Jia; Robert D Simpson; Jing Yuan; Zhenrong Xu; Wei Zhao; Salvacion Cacatian; Colin M Tice; Joan Guo; Alexey Ishchenko; Suresh B Singh; Zhongren Wu; Brian M McKeever; Yuri Bukhtiyarov; Judith A Johnson; Christopher P Doe; Richard K Harrison; Gerard M McGeehan; Lawrence W Dillard; John J Baldwin; David A Claremon
Journal:  ACS Med Chem Lett       Date:  2011-08-09       Impact factor: 4.345

Review 4.  Renin inhibitors as possible antihypertensive agents.

Authors:  K G Hofbauer; J M Wood
Journal:  Klin Wochenschr       Date:  1988-09-15

5.  The effect of aliskiren on the renal dysfunction following unilateral ureteral obstruction in the rat.

Authors:  Fayez T Hammad; Loay Lubbad
Journal:  Int J Physiol Pathophysiol Pharmacol       Date:  2016-08-05

6.  CGP 53437, an orally bioavailable inhibitor of human immunodeficiency virus type 1 protease with potent antiviral activity.

Authors:  E Alteri; G Bold; R Cozens; A Faessler; T Klimkait; M Lang; J Lazdins; B Poncioni; J L Roesel; P Schneider
Journal:  Antimicrob Agents Chemother       Date:  1993-10       Impact factor: 5.191

7.  Exploring the substructural space of indole-3-carboxamide derivatives binding to renin: a novel active-site spatial partitioning approach.

Authors:  Tao Jing; Jian Feng; Yumei Zuo; Boli Ran; Jianping Liu; Guoxiang He
Journal:  J Mol Model       Date:  2012-05-16       Impact factor: 1.810

Review 8.  A target safety assessment of the potential toxicological risks of targeting plasmepsin IX/X for the treatment of malaria.

Authors:  Jane Barber; Phumzile Sikakana; Claire Sadler; Delphine Baud; Jean-Pierre Valentin; Ruth Roberts
Journal:  Toxicol Res (Camb)       Date:  2021-02-15       Impact factor: 3.524

9.  TAK-272 (imarikiren), a novel renin inhibitor, improves cardiac remodeling and mortality in a murine heart failure model.

Authors:  Tomoya Hara; Satoshi Nishimura; Toshihiro Yamamoto; Yumiko Kajimoto; Keiji Kusumoto; Ray Kanagawa; Shota Ikeda; Tomoyuki Nishimoto
Journal:  PLoS One       Date:  2018-08-09       Impact factor: 3.240

Review 10.  The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction.

Authors:  Paolo Verdecchia; Fabio Angeli; Giovanni Mazzotta; Giorgio Gentile; Gianpaolo Reboldi
Journal:  Vasc Health Risk Manag       Date:  2008
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