Literature DB >> 33339534

Late-onset myocardial infarction and autoimmune haemolytic anaemia in a COVID-19 patient without respiratory symptoms, concomitant with a paradoxical increase in inflammatory markers: a case report.

Maria Chiara Pelle1, Bruno Tassone2, Marco Ricchio2, Maria Mazzitelli2, Chiara Davoli2, Giada Procopio2, Anna Cancelliere2, Valentina La Gamba2, Elena Lio2, Giovanni Matera3, Angela Quirino3, Giorgio Settimo Barreca4, Enrico Maria Trecarichi2, Carlo Torti2.   

Abstract

BACKGROUND: In December 2019, a new coronavirus (named severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) spread from China, causing a pandemic in a very short time. The main clinical presentation of SARS-CoV-2 infection (COVID-19, coronavirus disease-2019) is pneumonia, but several cardiovascular complications may also occur (e.g., acute coronary syndromes, pulmonary embolism, stroke, arrhythmias, heart failure and cardiogenic shock). Direct or indirect mechanisms induced by SARS-CoV-2 could be implicated in the pathogenesis of these events. CASE
PRESENTATION: We report herein the third case of COVID-19 autoimmune haemolytic anaemia (AIHA) reported so far, which occurredwithout any other possible explanations in a Caucasian patient. The patient also suffered from ST-elevation myocardial injury.
CONCLUSIONS: Both complications occurred quite late after COVID-19 diagnosis and were probably precipitated by systemic inflammation, as indicated by a significant delayed increase in inflammatory markers, including interleukin-6 (IL-6).

Entities:  

Keywords:  AIHA; Anaemia; COVID-19; Cardiovascular disease; IL-6; Inflammation

Mesh:

Substances:

Year:  2020        PMID: 33339534      PMCID: PMC7746982          DOI: 10.1186/s13256-020-02595-3

Source DB:  PubMed          Journal:  J Med Case Rep        ISSN: 1752-1947


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