Literature DB >> 33337581

Path from the discovery to the elimination of hepatitis C virus: Honoring the winners of the Nobel Prize in Physiology or Medicine 2020.

Ming-Lung Yu1,2,3,4, Wan-Long Chuang1,2.   

Abstract

The Nobel Prize for Physiology or Medicine, in the year 2020, has been awarded to three scientists, Harvey Alter, Michael Houghton, and Charles Rice, for jointly discovering the hepatitis C virus (HCV). This remarkable achievement is a huge breakthrough in the fight against hepatitis C. Most importantly, their pioneering works have successfully saved millions of lives by acting as the foundation for sensitive blood tests and effective antivirals. Inspired by the 2020 Nobel Prize winners, this review article honors their great efforts and discusses several unmet needs in the path toward HCV elimination. In Taiwan, we adopted a micro-elimination approach plus patient-centric outreach program to tackle the obstacles that stand in the way of HCV elimination. With its significant results, HCV elimination could be achieved in the near future.
© 2020 The Authors. The Kaohsiung Journal of Medical Sciences published by John Wiley & Sons Australia on behalf of Kaohsiung Medical University.

Entities:  

Keywords:  HCV; Nobel Prize; discovery; elimination

Year:  2020        PMID: 33337581     DOI: 10.1002/kjm2.12345

Source DB:  PubMed          Journal:  Kaohsiung J Med Sci        ISSN: 1607-551X            Impact factor:   2.744


  6 in total

1.  Anti-proliferative effects of the combination of Sulfamethoxazole and Quercetin via caspase3 and NFkB gene regulation: an in vitro and in vivo study.

Authors:  Heba Abd Elghany Sahyon; Eman N M Ramadan; Fayez Althobaiti; Mohammad M A Mashaly
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2022-01-07       Impact factor: 3.000

Review 2.  Integrating Management of Hepatitis C Infection into Primary Care: the Key to Hepatitis C Elimination Efforts.

Authors:  Allison E Wang; Eric Hsieh; Barbara J Turner; Norah Terrault
Journal:  J Gen Intern Med       Date:  2022-04-28       Impact factor: 6.473

3.  Revolution in the diagnosis and management of hepatitis C virus infection in current era.

Authors:  Farina M Hanif; Zain Majid; Nasir Hassan Luck; Abbas Ali Tasneem; Syed Muddasir Laeeq; Muhammed Mubarak
Journal:  World J Hepatol       Date:  2022-04-27

4.  Towards a safe hospital: hepatitis C in-hospital micro-elimination program (HCV-HELP study).

Authors:  Jee-Fu Huang; Ming-Yen Hsieh; Yu-Ju Wei; Jen-Yu Hung; Hsuan-Ti Huang; Ching-I Huang; Ming-Lun Yeh; Chung-Feng Huang; Tyng-Yuan Jang; Po-Yao Hsu; Po-Cheng Liang; Chia-Yen Dai; Zu-Yau Lin; Ming-Lung Yu; Wan-Long Chuang
Journal:  Hepatol Int       Date:  2021-11-30       Impact factor: 9.029

5.  Nationwide registry of glecaprevir plus pibrentasvir in the treatment of HCV in Taiwan.

Authors:  Chung-Feng Huang; Hsing-Tao Kuo; Te-Sheng Chang; Ching-Chu Lo; Chao-Hung Hung; Chien-Wei Huang; Lee-Won Chong; Pin-Nan Cheng; Ming-Lun Yeh; Cheng-Yuan Peng; Chien-Yu Cheng; Jee-Fu Huang; Ming-Jong Bair; Chih-Lang Lin; Chi-Chieh Yang; Szu-Jen Wang; Tsai-Yuan Hsieh; Tzong-Hsi Lee; Pei-Lun Lee; Wen-Chih Wu; Chih-Lin Lin; Wei-Wen Su; Sheng-Shun Yang; Chia-Chi Wang; Jui-Ting Hu; Lein-Ray Mo; Chun-Ting Chen; Yi-Hsiang Huang; Chun-Chao Chang; Chia-Sheng Huang; Guei-Ying Chen; Chien-Neng Kao; Chi-Ming Tai; Chun-Jen Liu; Mei-Hsuan Lee; Pei-Chien Tsai; Chia-Yen Dai; Jia-Horng Kao; Han-Chieh Lin; Wang-Long Chuang; Chi-Yi Chen; Kuo-Chih Tseng; Ming-Lung Yu
Journal:  Sci Rep       Date:  2021-12-06       Impact factor: 4.379

6.  Outreach onsite treatment with a simplified pangenotypic direct-acting anti-viral regimen for hepatitis C virus micro-elimination in a prison.

Authors:  Chun-Ting Chen; Ming-Ying Lu; Meng-Hsuan Hsieh; Pei-Chien Tsai; Tsai-Yuan Hsieh; Ming-Lun Yeh; Ching-I Huang; Yi-Shan Tsai; Yu-Min Ko; Ching-Chih Lin; Kuan-Yu Chen; Yu-Ju Wei; Po-Yao Hsu; Cheng-Ting Hsu; Tyng-Yuan Jang; Ta-Wei Liu; Po-Cheng Liang; Ming-Yen Hsieh; Zu-Yau Lin; Chung-Feng Huang; Jee-Fu Huang; Chia-Yen Dai; Wan-Long Chuang; Yu-Lueng Shih; Ming-Lung Yu
Journal:  World J Gastroenterol       Date:  2022-01-14       Impact factor: 5.742

  6 in total

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