| Literature DB >> 33334007 |
Ilaria Spassiani1, Lorenzo Gubian2, Giorgio Palù3, Giovanni Sebastiani4,5,6.
Abstract
SARS-CoV-2 is highly contagious, rapidly turned into a pandemic, and is causing a relevant number of critical to severe life-threatening COVID-19 patients. However, robust statistical studies of a large cohort of patients, potentially useful to implement a vaccination campaign, are rare. We analyzed public data of about 19,000 patients for the period 28 February to 15 May 2020 by several mathematical methods. Precisely, we describe the COVID-19 evolution of a number of variables that include age, gender, patient's care location, and comorbidities. It prompts consideration of special preventive and therapeutic measures for subjects more prone to developing life-threatening conditions while affording quantitative parameters for predicting the effects of an outburst of the pandemic on public health structures and facilities adopted in response. We propose a mathematical way to use these results as a powerful tool to face the pandemic and implement a mass vaccination campaign. This is done by means of priority criteria based on the influence of the considered variables on the probability of both death and infection.Entities:
Keywords: SARS-CoV-2; pandemic preparedness; statistical analysis; vaccines
Year: 2020 PMID: 33334007 DOI: 10.3390/vaccines8040766
Source DB: PubMed Journal: Vaccines (Basel) ISSN: 2076-393X