| Literature DB >> 33330803 |
Keiji Nakamura1, Satoshi Ide1, Sho Saito1, Noriko Kinoshita1, Satoshi Kutsuna1, Yuki Moriyama1, Tetsuya Suzuki1, Masayuki Ota1, Hidetoshi Nomoto1, Tetsuya Mizoue2, Masayuki Hojo3, Jin Takasaki3, Yusuke Asai4, Mari Terada1, Yutaro Akiyama1, Yusuke Miyazato1, Takato Nakamoto1, Yuji Wakimoto1, Mugen Ujiie1, Kei Yamamoto1, Masahiro Ishikane1, Shinichiro Morioka1, Kayoko Hayakawa1, Haruhito Sugiyama5, Norio Ohmagari1.
Abstract
Since the initial report of coronavirus disease (COVID-19) from the City of Wuhan, China in December 2019, there have been multiple cases globally. Reported here are 11 cases of COVID-19 at this hospital; all of the patients in question presented with relative bradycardia. The severity of the disease was classified into four grades. Of the patients studied, 3 with mild COVID-19 and 3 with moderate COVID-19 improved spontaneously. Lopinavir/ ritonavir was administered to 3 patients with severe COVID-19 and 2 with critical COVID-19. Both patients with critical COVID-19 required mechanical ventilation and extracorporeal membrane oxygenation. Both patients with critical COVID-19 had a higher fever that persisted for longer than patients with milder COVID-19. The respiratory status of patients with critical COVID-19 worsened rapidly 7 days after the onset of symptoms. Relative bradycardia may be useful in distinguishing between COVID-19 and bacterial community-acquired pneumonia. In patients who have had a fever for > 7 days, the condition might worsen suddenly. 2020, National Center for Global Health and Medicine.Entities:
Keywords: COVID-19; SARS-CoV-2; pneumonia
Year: 2020 PMID： 33330803 PMCID： PMC7731267 DOI： 10.35772/ghm.2020.01054
Source DB: PubMed Journal: Glob Health Med ISSN： 2434-9186