Literature DB >> 33327952

Publisher Correction: Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome.

Lee Shaashua1, Anabel Eckerling1, Boaz Israeli1, Gali Yanovich2, Ella Rosenne1, Suzana Fichman-Horn3, Ido Ben Zvi4, Liat Sorski1, Rita Haldar1, Ronit Satchi-Fainaro5, Tamar Geiger2, Erica K Sloan6, Shamgar Ben-Eliyahu7.   

Abstract

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Year:  2020        PMID: 33327952      PMCID: PMC7745392          DOI: 10.1186/s12915-020-00932-y

Source DB:  PubMed          Journal:  BMC Biol        ISSN: 1741-7007            Impact factor:   7.431


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Correction to: BMC Biol 18, 163 (2020) https://doi.org/10.1186/s12915-020-00893-2 The original publication of this article [1] contained an incorrect version of figure 4, and an incorrect version of figure S4 in Additional file 1. The wrong version of both files, which contained an incorrect color legend, was accidentally used during typesetting of the article. In this correction article the correct and incorrect version of figure 4 are published along with the updated Additional file 1. The original article has been updated. Incorrect figure 4. Correct Figure 4.
Fig. 4

Associations between levels of Serpin E1, IL-8, MIF, and PDGF-AA and survival in breast cancer patients. The METABRIC dataset was used to assess the association between expression levels of Serpin E1 (a), IL-8 (b), PDGF-AA (c), MIF (d) and the mean signature levels of all 4 factors (median of the mean of normalized expression levels of the four factors) (e), with 10-year survival. Protein levels were classified as higher or lower than the median, and the association to 10-year survival was assessed by the Kaplan-Meier analysis (n = 952 per group). p value was calculated using two-sided log rank test

Associations between levels of Serpin E1, IL-8, MIF, and PDGF-AA and survival in breast cancer patients. The METABRIC dataset was used to assess the association between expression levels of Serpin E1 (a), IL-8 (b), PDGF-AA (c), MIF (d) and the mean signature levels of all 4 factors (median of the mean of normalized expression levels of the four factors) (e), with 10-year survival. Protein levels were classified as higher or lower than the median, and the association to 10-year survival was assessed by the Kaplan-Meier analysis (n = 952 per group). p value was calculated using two-sided log rank test Additional file 1: Fig. S1. Excision of the primary tumor elicits gradual regression of early-stage metastases. Table S1. Cytokines pointed out by the cytokine array. Fig. S2. ELISA validation of in-vitro tumor secretion of the chosen cytokines. Fig. S3. Elevated levels of Serpin E1, IL-8, MIF and PDGF-AA are correlated to poor survival in lung cancer patients. Fig. S4. Associations between levels of DKK1, IL-6, M-CSF and LIF and survival in breast cancer patients.
  1 in total

1.  Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome.

Authors:  Lee Shaashua; Anabel Eckerling; Boaz Israeli; Gali Yanovich; Ella Rosenne; Suzana Fichman-Horn; Ido Ben Zvi; Liat Sorski; Rita Haldar; Ronit Satchi-Fainaro; Tamar Geiger; Erica K Sloan; Shamgar Ben-Eliyahu
Journal:  BMC Biol       Date:  2020-11-06       Impact factor: 7.431

  1 in total

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