Literature DB >> 33326762

Paying a Price Twice: Dose-Dependent Effects of Treg Cell-Derived TGF- β on Tolerance.

Hailey Brown1, Daria Esterházy2.   

Abstract

Although many immune cells can secrete TGF-β, whether all sources of TGF-β are functionally equivalent is unknown. In this issue, Turner et al. uncover the importance of T regulatory (Treg) cell-intrinsic Tgfb1 gene dose in the prevention of autoimmunity and allergic disease.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 33326762     DOI: 10.1016/j.immuni.2020.11.008

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  1 in total

1.  Anti-PD-L1/TGF-βR fusion protein (SHR-1701) overcomes disrupted lymphocyte recovery-induced resistance to PD-1/PD-L1 inhibitors in lung cancer.

Authors:  Bo Cheng; Kaikai Ding; Pengxiang Chen; Jianxiong Ji; Tao Luo; Xiaofan Guo; Wei Qiu; Chunhong Ma; Xue Meng; Jian Wang; Jinming Yu; Yuan Liu
Journal:  Cancer Commun (Lond)       Date:  2022-01-03
  1 in total

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