C Hopkins1, P Surda1, L A Vaira2, J R Lechien3, M Safarian1, S Saussez4, N Kumar5. 1. Guy's Hospital, London, UK. 2. University of Sassari, Italy. 3. CHU Saint-Pierre, Belgium. 4. University of Mons, Belgium. 5. Wrightington, Wigan and Leigh Teaching NHS FT, UK.
Abstract
INTRODUCTION: Loss of smell and taste is now recognised as amongst the most common symptoms of COVID-19 and the best predictor of COVID-19 positivity. Long term outcomes are unknown. This study aims to investigate recovery of loss of smell and the prevalence of parosmia. METHODOLOGY: 6-month follow-up of respondents to an online surgery who self-reported loss of smell at the onset of the CO- VID-19 pandemic in the UK. Information of additional symptoms, recovery of loss of smell and the development of parosmia was collected. RESULTS: 44% of respondents reported at least one other ongoing symptom at 6 months, of which fatigue (n=106) was the most prevalent. There was a significant improvement in self-rating of severity of olfactory loss where 177 patients stated they had a normal smell of smell while 12 patients reported complete loss of smell. The prevalence of parosmia is 43.1% with median interval of 2.5 months (range 0-6) from the onset of loss of smell. CONCLUSIONS: While many patients recover quickly, some experience long-term deficits with no self-reported improvement at 6 months. Furthermore, there is a high prevalence of parosmia even in those who report at least some recovery of olfactory func- tion. Longer term evaluation of recovery is required.
INTRODUCTION: Loss of smell and taste is now recognised as amongst the most common symptoms of COVID-19 and the best predictor of COVID-19 positivity. Long term outcomes are unknown. This study aims to investigate recovery of loss of smell and the prevalence of parosmia. METHODOLOGY: 6-month follow-up of respondents to an online surgery who self-reported loss of smell at the onset of the CO- VID-19 pandemic in the UK. Information of additional symptoms, recovery of loss of smell and the development of parosmia was collected. RESULTS: 44% of respondents reported at least one other ongoing symptom at 6 months, of which fatigue (n=106) was the most prevalent. There was a significant improvement in self-rating of severity of olfactory loss where 177 patients stated they had a normal smell of smell while 12 patients reported complete loss of smell. The prevalence of parosmia is 43.1% with median interval of 2.5 months (range 0-6) from the onset of loss of smell. CONCLUSIONS: While many patients recover quickly, some experience long-term deficits with no self-reported improvement at 6 months. Furthermore, there is a high prevalence of parosmia even in those who report at least some recovery of olfactory func- tion. Longer term evaluation of recovery is required.
Authors: Ludger Klimek; Jan Hagemann; Julia Döge; Laura Freudelsperger; Mandy Cuevas; Felix Klimek; Thomas Hummel Journal: Allergo J Int Date: 2022-06-20
Authors: Luigi Angelo Vaira; Jerome R Lechien; Mohamad Khalife; Marzia Petrocelli; Stephane Hans; Lea Distinguin; Giovanni Salzano; Marco Cucurullo; Piero Doneddu; Francesco Antonio Salzano; Federico Biglioli; Fabrice Journe; Andrea Fausto Piana; Giacomo De Riu; Sven Saussez Journal: Pathogens Date: 2021-01-12
Authors: Sven Saussez; Luigi Angelo Vaira; Carlos M Chiesa-Estomba; Serge-D Le Bon; Mihaela Horoi; Giovanna Deiana; Marzia Petrocelli; Philippe Boelpaep; Giovanni Salzano; Mohamad Khalife; Stephane Hans; Giacomo De Riu; Claire Hopkins; Jerome R Lechien Journal: Pathogens Date: 2021-06-04