Literature DB >> 33315326

Payment incentives and the use of higher-cost drugs: a retrospective cohort analysis of intravenous iron in the Medicare population.

Bryan C Hambley, Kelly E Anderson1, Satish P Shanbhag, Aditi P Sen, Gerard Anderson.   

Abstract

OBJECTIVES: Medicare Part B payment methods incentivize the use of more expensive injectable and infused drugs. We examined prescribing patterns in the context of intravenous (IV) iron, for which multiple similarly safe and efficacious formulations exist, with wide variations in price. STUDY
DESIGN: We conducted a retrospective cohort analysis of IV iron utilization and payment in the Medicare population between 2015 and 2017.
METHODS: This analysis used a national, random 20% sample of Medicare fee-for-service beneficiaries with Part B claims for IV iron between January 2015 and December 2017-a period before, during, and after a national shortage of iron dextran. This sample included 66,710 Medicare fee-for-service beneficiaries with at least 1 Part B claim for IV iron.
RESULTS: The greatest increase in utilization occurred in the most expensive iron formulation, ferric carboxymaltose; its market share rose from 27.4% of use in 2015 to 47.7% in 2017. The use of a less expensive formulation, iron dextran, decreased from 26.7% to 18.7% over the same period. An alternative payment model in Maryland hospitals was associated with markedly less utilization of ferric carboxymaltose, accounting for 4.7% of IV iron utilization in Maryland hospitals.
CONCLUSIONS: There was an increase in the dispensing of a higher-priced IV iron formulation associated with a shortage of a less expensive drug that persisted once the shortage ended. These findings in IV iron have broader implications for Part B drug payment policy because the price of the drug determines the physician and health system payment.

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Year:  2020        PMID: 33315326      PMCID: PMC8863336          DOI: 10.37765/ajmc.2020.88539

Source DB:  PubMed          Journal:  Am J Manag Care        ISSN: 1088-0224            Impact factor:   2.229


  16 in total

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Authors:  M Auerbach; K Al Talib
Journal:  Kidney Int       Date:  2008-03       Impact factor: 10.612

2.  ASHP guidelines on managing drug product shortages.

Authors:  Erin R Fox; Milena M McLaughlin
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Review 3.  Safety of intravenous iron formulations: facts and folklore.

Authors:  Michael Auerbach; Iain C Macdougall
Journal:  Blood Transfus       Date:  2014-07       Impact factor: 3.443

4.  Use of Bone-Modifying Agents Among Medicare Beneficiaries With Multiple Myeloma.

Authors:  Arjun Gupta; Peiqi Wang; Syed Abbas Ali; S Vincent Rajkumar; Bishal Gyawali; Heidi N Overton; Martin A Makary
Journal:  JAMA Oncol       Date:  2020-02-01       Impact factor: 31.777

Review 5.  The available intravenous iron formulations: History, efficacy, and toxicology.

Authors:  Michael Auerbach; Iain Macdougall
Journal:  Hemodial Int       Date:  2017-03-29       Impact factor: 1.812

Review 6.  Single-dose intravenous iron for iron deficiency: a new paradigm.

Authors:  Michael Auerbach; Thomas Deloughery
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2016-12-02

7.  Validation of a combined comorbidity index.

Authors:  M Charlson; T P Szatrowski; J Peterson; J Gold
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8.  Iron deficiency after Roux-en-Y gastric bypass: insufficient iron absorption from oral iron supplements.

Authors:  Ina Gesquiere; Matthias Lannoo; Patrick Augustijns; Christophe Matthys; Bart Van der Schueren; Veerle Foulon
Journal:  Obes Surg       Date:  2014-01       Impact factor: 4.129

9.  Despite Federal Legislation, Shortages Of Drugs Used In Acute Care Settings Remain Persistent And Prolonged.

Authors:  Serene I Chen; Erin R Fox; M Kennedy Hall; Joseph S Ross; Emily M Bucholz; Harlan M Krumholz; Arjun K Venkatesh
Journal:  Health Aff (Millwood)       Date:  2016-05-01       Impact factor: 6.301

10.  Comparative safety of intravenous ferumoxytol versus ferric carboxymaltose in iron deficiency anemia: A randomized trial.

Authors:  N Franklin Adkinson; William E Strauss; Iain C Macdougall; Kristine E Bernard; Michael Auerbach; Robert F Kaper; Glenn M Chertow; Julie S Krop
Journal:  Am J Hematol       Date:  2018-02-24       Impact factor: 10.047

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  2 in total

Review 1.  Ironing It All Out: A Comprehensive Review of Iron Deficiency Anemia in Inflammatory Bowel Disease Patients.

Authors:  Laura A Maas; Mahesh Krishna; Alyssa M Parian
Journal:  Dig Dis Sci       Date:  2022-08-05       Impact factor: 3.487

2.  Prescribing of low- versus high-cost Part B drugs in Medicare Advantage and traditional Medicare.

Authors:  Kelly E Anderson; Daniel Polsky; Sydney Dy; Aditi P Sen
Journal:  Health Serv Res       Date:  2021-12-14       Impact factor: 3.734

  2 in total

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