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Literature DB >> 33315144

Full genome sequence of bovine alphaherpesvirus 2 (BoHV-2).

Florian Pfaff¹, Antonie Neubauer-Juric², Stefan Krebs³, Andreas Hauser³, Stefanie Singer², Helmut Blum³, Bernd Hoffmann⁴.

Abstract

We present the complete genome sequence of bovine alphaherpesvirus 2 (BoHV-2), a member of the family Herpesviridae, subfamily Alphaherpesvirinae, genus Simplexvirus. BoHV-2 is the causative agent of bovine ulcerative mammillitis (bovine herpes mammillitis) and pseudo-lumpy skin disease. The genomic architecture of BoHV-2 is typical of most simplexvirus genomes and congruent with that of human alphaherpesvirus 1 (HHV-1). The genome comprises a total of 131,245 base pairs and has an overall G+C content of 64.9 mol%. A total of 75 open reading frames are predicted. The gene repertoire of BoHV-2 is analogous to that of HHV-1, although the coding region of US12 is missing. A phylogenetic analysis supported BoHV-2 as a member of the genus Simplexvirus.

Entities: Disease Gene Species

Year: 2020 PMID： 33315144 DOI： 10.1007/s00705-020-04895-x

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

17 in total

1. Isolation of bovine herpesvirus-2 (BHV-2) from a case of pseudo-lumpy skin disease in the United Kingdom.

Authors: J A Woods; J A Herring; P F Nettleton; N Kreuger; F M Scott; H W Reid
Journal: Vet Rec Date: 1996-02-03 Impact factor: 2.695

2. Anatomy of bovine mammillitis DNA. I Restriction endonuclease maps of four populations of molecules that differ in the relative orientation of their long and short components.

Authors: T G Buchman; B Roizman
Journal: J Virol Date: 1978-01 Impact factor: 5.103

7. Conservation of a gene cluster including glycoprotein B in bovine herpesvirus type 2 (BHV-2) and herpes simplex virus type 1 (HSV-1).

Authors: W Hammerschmidt; F Conraths; J Mankertz; G Pauli; H Ludwig; H J Buhk
Journal: Virology Date: 1988-08 Impact factor: 3.616

Full genome sequence of bovine alphaherpesvirus 2 (BoHV-2).

1. Isolation of bovine herpesvirus-2 (BHV-2) from a case of pseudo-lumpy skin disease in the United Kingdom.

2. Anatomy of bovine mammillitis DNA. I Restriction endonuclease maps of four populations of molecules that differ in the relative orientation of their long and short components.

3. Anatomy of bovine mammillitis DNA II. Size and arrangements of the deoxynucleotide sequences.

4. Characteristics of bovine mammillitis virus.

5. Bovine ulcerative mammillitis caused by a herpesvirus.

6. Molecular phylogeny of the alphaherpesvirinae subfamily and a proposed evolutionary timescale.

7. Conservation of a gene cluster including glycoprotein B in bovine herpesvirus type 2 (BHV-2) and herpes simplex virus type 1 (HSV-1).

8. Latent infection of cattle with bovid herpesvirus 2.

9. Atypical bovine herpes mammillitis affecting cows and calves.

10. Isolation and characterisation of bovine herpesvirus mammillitis virus and its pathogenicity for cattle.