| Literature DB >> 33310018 |
Pamali Fonseka1, Mohashin Pathan1, Sai V Chitti1, Taeyoung Kang1, Suresh Mathivanan2.
Abstract
High-throughput methods to profile the genome, transcriptome, proteome and metabolome of various systems has become a routine in multiple research laboratories around the world. Hence, to analyse and interpret these heterogenous datasets user-friendly bioinformatics tools are needed. Here, we discuss FunRich tool that enables biologists to perform functional enrichment analysis on the generated datasets. Users can perform enrichment analysis with a variety of background databases and have complete control in updating or modifying the content in most of the databases. Specifically, users can download and update the background database from UniProt at any time thereby allowing a robust background database that can support annotations from >18 taxonomies. Users can create customizable Venn diagrams, pie charts, bar graphs and heatmaps of publication quality for their datasets using FunRich (http://www.funrich.org). Overall, FunRich tool is user-friendly and enables users to perform various analysis on their datasets with minimal or no aid from bioinformaticians.Keywords: FunRich; Venn diagram; gene set enrichment; heatmap; vesiclepedia
Year: 2020 PMID: 33310018 DOI: 10.1016/j.jmb.2020.166747
Source DB: PubMed Journal: J Mol Biol ISSN: 0022-2836 Impact factor: 5.469