Bo Dong1,2,3, Gaoqiang Zhang4, Jiajia Zhang5, Junyu Bai4, Weiming Lin6,7,8. 1. College of Life Science of Longyan University, Longyan, 364012, China. bodong1983@qq.com. 2. Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology, Longyan, 364012, China. bodong1983@qq.com. 3. Longyan University Animal Hospital, Longyan, 364012, China. bodong1983@qq.com. 4. College of Life Science of Longyan University, Longyan, 364012, China. 5. Shenzhen An An Animal Hospital, Shenzhen, 518000, China. 6. College of Life Science of Longyan University, Longyan, 364012, China. wmlin925@126.com. 7. Fujian Provincial Key Laboratory for the Prevention and Control of Animal Infectious Diseases and Biotechnology, Longyan, 364012, China. wmlin925@126.com. 8. Longyan University Animal Hospital, Longyan, 364012, China. wmlin925@126.com.
Abstract
BACKGROUND: Canine parvovirus 2 (CPV-2) is a pathogenic virus that infects dogs, causing a highly infectious disease. Monitoring CPV-2 spread is an important part of prevention; however, the prevalence and epidemiological characteristics of CPV-2 have not been systematically evaluated and analyzed in mainland China. Therefore, a systematic review and meta-analysis were performed to assess prevalence and epidemiological characteristics of CPV-2 in domestic dogs in mainland China. METHODS: In this study, Chinese and English literature on CPV-2 epidemiology published between January 2006 and December 2019 was evaluated. Regarding meta-analysis, the random-effect model was employed by forest plot with 95% of confidence interval. The number of CPV-2 infections was identified and the pooled prevalence of infection, as well as the epidemiological characteristics, was calculated using meta-analysis. RESULTS: A total of 39 studies (data from 137,844 dogs) met the evaluation criteria and were used in our study. The pooled prevalence of CPV-2 infection in mainland China was 36%. CPV-2 infection were associated with age, breed, sampling season and immunization status, but not with gender, publication time and diagnostic methods. CONCLUSIONS: Our results indicated that CPV-2 is prevalent among dogs in China. It is therefore necessary to carry out continuous surveillance and epidemiological studies of CPV-2. In addition, accordingly, effective measures should be taken to prevent the transmission and spread of CPV-2 among the Chinese dog population.
BACKGROUND:Canine parvovirus 2 (CPV-2) is a pathogenic virus that infects dogs, causing a highly infectious disease. Monitoring CPV-2 spread is an important part of prevention; however, the prevalence and epidemiological characteristics of CPV-2 have not been systematically evaluated and analyzed in mainland China. Therefore, a systematic review and meta-analysis were performed to assess prevalence and epidemiological characteristics of CPV-2 in domestic dogs in mainland China. METHODS: In this study, Chinese and English literature on CPV-2 epidemiology published between January 2006 and December 2019 was evaluated. Regarding meta-analysis, the random-effect model was employed by forest plot with 95% of confidence interval. The number of CPV-2 infections was identified and the pooled prevalence of infection, as well as the epidemiological characteristics, was calculated using meta-analysis. RESULTS: A total of 39 studies (data from 137,844 dogs) met the evaluation criteria and were used in our study. The pooled prevalence of CPV-2 infection in mainland China was 36%. CPV-2 infection were associated with age, breed, sampling season and immunization status, but not with gender, publication time and diagnostic methods. CONCLUSIONS: Our results indicated that CPV-2 is prevalent among dogs in China. It is therefore necessary to carry out continuous surveillance and epidemiological studies of CPV-2. In addition, accordingly, effective measures should be taken to prevent the transmission and spread of CPV-2 among the Chinese dog population.
Authors: Esam I Azhar; Sherif A El-Kafrawy; Suha A Farraj; Ahmed M Hassan; Muneera S Al-Saeed; Anwar M Hashem; Tariq A Madani Journal: N Engl J Med Date: 2014-06-04 Impact factor: 91.245
Authors: Hana A Pawestri; Arie A Nugraha; Alvin X Han; Eka Pratiwi; Edyth Parker; Mathilde Richard; Stefan van der Vliet; Ron A M Fouchier; David H Muljono; Menno D de Jong; Vivi Setiawaty; Dirk Eggink Journal: Virus Genes Date: 2020-06-01 Impact factor: 2.332