Literature DB >> 33306497

Polycystic Ovarian Syndrome Genetics and Epigenetics.

Joshua C Combs1,2, Micah J Hill1,2, Alan H Decherney1.   

Abstract

Polycystic ovarian syndrome and its associated endocrine abnormalities comprise one of the most common metabolic spectrum disorders within the human race. Because of the variance in phenotypic expression among individuals and within family lineages, attention has been turned to genetic and epigenetic changes in which the root cause of the disorder may lie. Further understanding of DNA/histone methylation and microRNA patterns may help to improve the accuracy of diagnosis and lead to future treatment options.
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Year:  2021        PMID： 33306497      PMCID： PMC7855879          DOI： 10.1097/GRF.0000000000000581

Source DB:  PubMed          Journal:  Clin Obstet Gynecol        ISSN： 0009-9201            Impact factor:   1.966


  20 in total

1.  The fetal and infant origins of adult disease.

Authors:  D J Barker
Journal:  BMJ       Date:  1990-11-17

Review 2.  Small but smart--microRNAs in the centre of inflammatory processes during cardiovascular diseases, the metabolic syndrome, and ageing.

Authors:  Blanche Schroen; Stephane Heymans
Journal:  Cardiovasc Res       Date:  2011-10-11       Impact factor: 10.787

Review 3.  Polycystic ovarian syndrome.

Authors:  Subbulaxmi Trikudanathan
Journal:  Med Clin North Am       Date:  2014-11-22       Impact factor: 5.456

4.  Introduction: Determinants of polycystic ovary syndrome.

Authors:  Ricardo Azziz
Journal:  Fertil Steril       Date:  2016-05-26       Impact factor: 7.329

5.  Hypomethylation of the LH/choriogonadotropin receptor promoter region is a potential mechanism underlying susceptibility to polycystic ovary syndrome.

Authors:  Peng Wang; Han Zhao; Tao Li; Wei Zhang; Keliang Wu; Mei Li; Yuehong Bian; Hongbin Liu; Yunna Ning; Guangyu Li; Zi-Jiang Chen
Journal:  Endocrinology       Date:  2014-02-14       Impact factor: 4.736

Review 6.  Mitochondrial dysfunction: An emerging link in the pathophysiology of polycystic ovary syndrome.

Authors:  Pallavi Shukla; Srabani Mukherjee
Journal:  Mitochondrion       Date:  2020-02-17       Impact factor: 4.160

7.  Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype.

Authors:  Jan M McAllister; Bhavi Modi; Bruce A Miller; Jessica Biegler; Richard Bruggeman; Richard S Legro; Jerome F Strauss
Journal:  Proc Natl Acad Sci U S A       Date:  2014-03-31       Impact factor: 11.205

Review 8.  Pathomechanisms of polycystic ovary syndrome: Multidimensional approaches.

Authors:  Pooja Sagvekar; Roshan Dadachanji; Krutika Patil; Srabani Mukherjee
Journal:  Front Biosci (Elite Ed)       Date:  2018-03-01

9.  Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys.

Authors:  Ning Xu; Soonil Kwon; David H Abbott; David H Geller; Daniel A Dumesic; Ricardo Azziz; Xiuqing Guo; Mark O Goodarzi
Journal:  PLoS One       Date:  2011-11-04       Impact factor: 3.240

10.  Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell.

Authors:  Jiawei Xu; Xiao Bao; Zhaofeng Peng; Linlin Wang; Linqing Du; Wenbin Niu; Yingpu Sun
Journal:  Oncotarget       Date:  2016-05-10
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