Literature DB >> 33302376

Compliant Nano-Pliers as a Biomedical Tool at the Nanoscale: Design, Simulation and Fabrication.

Alessio Buzzin1, Serena Cupo2, Ennio Giovine3, Giampiero de Cesare1, Nicola Pio Belfiore2.   

Abstract

This paper presents the development of a multi-hinge, multi-DoF (Degrees of Freedom) nanogripper actuated by means of rotary comb drives and equipped with CSFH (Conjugate Surface Flexure Hinges), with the goal of performing complex in-plane movements at the nanoscale. The design approach, the simulation and a specifically conceived single-mask fabrication process are described in detail and the achieved results are illustrated by SEM images. The first prototype presents a total overall area of (550 × 550) μm2, an active clamping area of (2 × 4) μm2, 600 nm-wide circular curved beams as flexible hinges for its motion and an aspect ratio of about 2.5. These features allow the proposed system to grasp objects a few hundred nanometers in size.

Entities:  

Keywords:  Lab-on-Chip; MEMS; NEMS; amorphous silicon; conjugate surfaces flexure hinge; four-bar linkage; nanogripper; rotary comb drive

Year:  2020        PMID: 33302376      PMCID: PMC7762596          DOI: 10.3390/mi11121087

Source DB:  PubMed          Journal:  Micromachines (Basel)        ISSN: 2072-666X            Impact factor:   2.891


  9 in total

Review 1.  Advances in top-down and bottom-up surface nanofabrication: techniques, applications & future prospects.

Authors:  Abhijit Biswas; Ilker S Bayer; Alexandru S Biris; Tao Wang; Enkeleda Dervishi; Franz Faupel
Journal:  Adv Colloid Interface Sci       Date:  2011-11-16       Impact factor: 12.984

Review 2.  Microrobots for minimally invasive medicine.

Authors:  Bradley J Nelson; Ioannis K Kaliakatsos; Jake J Abbott
Journal:  Annu Rev Biomed Eng       Date:  2010-08-15       Impact factor: 9.590

3.  Tetherless thermobiochemically actuated microgrippers.

Authors:  Timothy G Leong; Christina L Randall; Bryan R Benson; Noy Bassik; George M Stern; David H Gracias
Journal:  Proc Natl Acad Sci U S A       Date:  2009-01-12       Impact factor: 11.205

4.  Highly Disordered Array of Silicon Nanowires: an Effective and Scalable Approach for Performing and Flexible Electrochemical Biosensors.

Authors:  Luca Maiolo; Davide Polese; Alessandro Pecora; Guglielmo Fortunato; Yosi Shacham-Diamand; Annalisa Convertino
Journal:  Adv Healthc Mater       Date:  2015-12-30       Impact factor: 9.933

5.  Multiwell cartridge with integrated array of amorphous silicon photosensors for chemiluminescence detection: development, characterization and comparison with cooled-CCD luminograph.

Authors:  Mara Mirasoli; Augusto Nascetti; Domenico Caputo; Martina Zangheri; Riccardo Scipinotti; Luca Cevenini; Giampiero de Cesare; Aldo Roda
Journal:  Anal Bioanal Chem       Date:  2014-06-26       Impact factor: 4.142

6.  Biopsy using a magnetic capsule endoscope carrying, releasing, and retrieving untethered microgrippers.

Authors:  Sehyuk Yim; Evin Gultepe; David H Gracias; Metin Sitti
Journal:  IEEE Trans Biomed Eng       Date:  2014-02       Impact factor: 4.538

7.  Design of a Novel MEMS Microgripper with Rotatory Electrostatic Comb-Drive Actuators for Biomedical Applications.

Authors:  Luis A Velosa-Moncada; Luz Antonio Aguilera-Cortés; Max A González-Palacios; Jean-Pierre Raskin; Agustin L Herrera-May
Journal:  Sensors (Basel)       Date:  2018-05-22       Impact factor: 3.576

8.  Controlling DNA Bundle Size and Spatial Arrangement in Self-assembled Arrays on Superhydrophobic Surface.

Authors:  Gabriele Ciasca; Massimiliano Papi; Valentina Palmieri; Michela Chiarpotto; Simone Di Claudio; Adele De Ninno; Ennio Giovine; Gaetano Campi; Annamaria Gerardino; Luca Businaro; Marco De Spirito
Journal:  Nanomicro Lett       Date:  2014-12-30

9.  Grasping and Releasing Agarose micro Beads in Water Drops.

Authors:  Federica Vurchio; Pietro Ursi; Alessio Buzzin; Andrea Veroli; Andrea Scorza; Matteo Verotti; Salvatore Andrea Sciuto; Nicola Pio Belfiore
Journal:  Micromachines (Basel)       Date:  2019-06-30       Impact factor: 2.891

  9 in total

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